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Transfusion Clinique et Biologique, 2010
Since its discovery in the 17th century, the red blood cell, recognized in time as the critical cell component for survival, has been the focus of much attention. Its unique role in gas exchange (oxygen/CO(2) transport) and its distinct characteristics (absence of nucleus; biconcave cell shape) together with an - in essence - unlimited supply lead to ...
Pasini, E., Mann, M., Thomas, A.
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Since its discovery in the 17th century, the red blood cell, recognized in time as the critical cell component for survival, has been the focus of much attention. Its unique role in gas exchange (oxygen/CO(2) transport) and its distinct characteristics (absence of nucleus; biconcave cell shape) together with an - in essence - unlimited supply lead to ...
Pasini, E., Mann, M., Thomas, A.
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Clinics in Laboratory Medicine, 2021
Red blood cell (RBC) transfusions are necessary to increase a patient's oxygen carrying capacity. The optimal transfusion trigger remains elusive, but a restrictive transfusion trigger of 7 g/dL has been shown in studies to reduce RBC transfusions without adversely affecting patient outcomes.
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Red blood cell (RBC) transfusions are necessary to increase a patient's oxygen carrying capacity. The optimal transfusion trigger remains elusive, but a restrictive transfusion trigger of 7 g/dL has been shown in studies to reduce RBC transfusions without adversely affecting patient outcomes.
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Red blood cell “aggregability”
Clinical Hemorheology and Microcirculation, 2009It is well understood that the extent of red blood cell (RBC) aggregation is determined by both plasmatic and cellular factors [10]. It is also clear that alterations of plasmatic and cellular factors may be related to separate disease processes [1]. For example, plasma composition may change (e.g., fibrinogen concentration increase) due to an acute ...
Oguz K, Baskurt, Herbert J, Meiselman
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Transfusion, 1973
A method used to increase the utilization of packed red blood cells and components is described. This required the staff of the blood center to visit hospital staff meetings and explain the use of platelet concentrates, cryoprecipitates, fresh frozen plasma, leukocyte‐poor blood, and packed red blood cells.
G A, Becker, R H, Aster
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A method used to increase the utilization of packed red blood cells and components is described. This required the staff of the blood center to visit hospital staff meetings and explain the use of platelet concentrates, cryoprecipitates, fresh frozen plasma, leukocyte‐poor blood, and packed red blood cells.
G A, Becker, R H, Aster
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The International Journal of Biochemistry & Cell Biology, 2002
Red blood cells are derived from haemopoietic stem cells in bone marrow. Following a series of maturation steps, directed largely by the hormone erythropoietin (Epo), red cells enucleate and enter the circulatory system. In circulation these small, flexible biconcave cells containing haemoglobin transport O(2) from the lungs to the periphery, and CO(2)
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Red blood cells are derived from haemopoietic stem cells in bone marrow. Following a series of maturation steps, directed largely by the hormone erythropoietin (Epo), red cells enucleate and enter the circulatory system. In circulation these small, flexible biconcave cells containing haemoglobin transport O(2) from the lungs to the periphery, and CO(2)
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Artificial Cells, Blood Substitutes, and Biotechnology, 1998
Soluble polymerized haemoglobin (polyhaemoglobin) is now in a phase III clinical trials. Patients have received up to 20 units (10 litres) in trauma surgery and other surgery. Polyhaemoglobin can be stored for more than 1 year. Haemoglobin solutions have no blood group antigen and can be used as a 'universal donor' oxygen carrier.
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Soluble polymerized haemoglobin (polyhaemoglobin) is now in a phase III clinical trials. Patients have received up to 20 units (10 litres) in trauma surgery and other surgery. Polyhaemoglobin can be stored for more than 1 year. Haemoglobin solutions have no blood group antigen and can be used as a 'universal donor' oxygen carrier.
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Survey of Anesthesiology, 1969
AS an essential therapeutic agent in modern medical practice, human blood is clearly a valuable and limited natural resource. The total use of blood grows annually, as does the difficulty of procuring it in amounts sufficient to meet expanding needs.
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AS an essential therapeutic agent in modern medical practice, human blood is clearly a valuable and limited natural resource. The total use of blood grows annually, as does the difficulty of procuring it in amounts sufficient to meet expanding needs.
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