Results 31 to 40 of about 1,156,998 (251)

Neonatal red blood cell transfusion [PDF]

open access: yesVox Sanguinis, 2020
Transfusions are more common in premature infants with approximately 40% of low birth weight infants and up to 90% of extremely low birth weight infants requiring red blood cell transfusion. Although red blood cell transfusion can be life‐saving in these preterm infants, it has been associated with higher rates of complications including necrotizing ...
Andréanne, Villeneuve   +3 more
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Production of hematopoietic cells from umbilical cord blood stem cells for transfusion purposes: Focus on ex vivo generation of red blood cells [PDF]

open access: yesScripta Medica, 2012
Cord blood contains a heterogeneous population of stem cells and progenitors and, in addition to transplantation these cells could be used also for ex vivo production of mature cells, as red blood cells (RBC).
Ivanović Zoran, Vlaski Marija
doaj  

Changes in Hematological and Hemorheological Parameters Following Mild COVID-19: A 4-Month Follow-Up Study

open access: yesHematology Reports, 2023
Background: Coronavirus Disease 2019 (COVID-19) was described to affect red blood cells (RBC) in both severe and mild disease courses. The aim of this study was to investigate whether hematological and hemorheological changes that were previously ...
Janina Bros   +7 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Clustered Red Blood Cells Splitting via Boundary Analysis in Microscopic Thin Blood Smear Digital Images

open access: yesInternational Journal of Technology, 2015
Clustered Red Blood Cells are observed very frequently in the thin blood smear digital images. Separating clustered Red Blood Cells from the single Red Blood Cells and splitting of clustered Red Blood Cells into single Red Blood Cells is a challenging
Naveed Abbas   +3 more
doaj   +1 more source

Effects of intraoperative blood salvage on red blood cells

open access: yesZhongguo shuxue zazhi, 2022
Intraoperative blood salvage (IBS) is a life support technology that uses a series of artificial devices to treat the recycled blood during surgery, which then is transfused back into the patients.
Mingxia LIU, Yuanyuan YAO, Min YAN
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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