Results 61 to 70 of about 4,116,135 (338)

Rapid colour changes in Euglena sanguinea (Euglenophyceae) caused by internal lipid globule migration [PDF]

, 2018
The accumulation of red pigments under chronic stress is a response observed in most groups of oxygenic photoautotrophs. It is thought that the red pigments in the cell shield the chlorophyll located underneath from the light. Among these red pigments,
Abramoff M.D., Aitor Laza-Martínez, Beatriz Fernández-Marín, Dambeck M., Ehrenberg C.G., García-Plazaola J.I., Guiry M.D., Heidt K, José Ignacio García-Plazaola, Lohr M., Roach T., Ruggeri B.A.   +11 more
core   +2 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

A theory of a saliency map in primary visual cortex (V1) tested by psychophysics of color-orientation interference in texture segmentation [PDF]

, 2006
It has been proposed that V1 creates a bottom-up saliency map, where saliency of any location increases with the firing rate of the most active V1 output cell responding to it, regardless the feature selectivity of the cell.
Jingling, L., Zhaoping, L.
core  

Toxoplasma and Plasmodium protein kinases: roles in invasion and host cell remodelling [PDF]

, 2011
Some apicomplexan parasites have evolved distinct protein kinase families to modulate host cell structure and function. Toxoplasma gondii rhoptry protein kinases and pseudokinases are involved in virulence and modulation of host cell signalling.
Abdi, Agarwal, Allen, Anamika, Behnke, Billker, Billker, Bishop, Blethrow, Bracchi-Ricard, Bradley, Brian M. Cooke, Butcher, Carruthers, Carvalho, Christian Doerig, Cooke, Cooke, Coppi, Dalpke, Daniel C. Lim, Dar, Doerig, Doerig, Doerig, Dorin, Dorin, Dorin, Droucheau, El Hajj, Fennell, Fentress, Gilbert, Green, Gueirard, Halbert, Hanks, Huse, Hutti, Ishino, Jensen, Jeroen P.J. Saeij, Kafsack, Kannan, Kato, Khaminets, Khan, Khan, Khan, Kieschnick, Kun, Kuo, Labesse, Ling, Lodoen, Lourido, Luder, Manning, Martens, Melzer, Nagamune, Nunes, Nunes, Ojo, Ong, Parsons, Peixoto, Pernas, Qiu, Reese, Reese, Reese, Reininger, Reininger, Reininger, Rosenberg, Rosowski, Saeij, Saeij, Scheibel, Schneider, Shiels, Sicard, Singh, Singh, Solyakov, Sopko, Steinfeldt, Sugi, Suss-Toby, Taylor, Taylor, Tewari, Vaid, van de Sand, Ward, Ward, Wernimont, Wernimont, Xu, Yamamoto, Yasukawa, Zeqiraj, Zeqiraj, Zhao, Zhao   +105 more
core   +2 more sources

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Red Cell Phenotyping in Thalassemia Patient at Songklanagarind Hospital

Journal of Health Science and Medical Research (JHSMR), 2016
The purpose of this study was to determine the frequency of Rh, Kidd and Duffy phenotypes in thalassemia major patients with regular transfusion which may develop antibodies to red cell antigens that can be a significant complication of transfusion ...
Pornkanok Saksrisirisakul, Wanwimon Yindee, Nardsuda Thawornsuk   +2 more
doaj  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Blood volume changes [PDF]

Analysis of radionuclide volume determinations made for the crewmembers of selected Gemini and Apollo missions showed that orbital spaceflight has an effect on red cell mass.
Driscoll, T. B., Johnson, P. C., Leblance, A. D.   +2 more
core   +1 more source

A fractal approach to the rheology of concentrated cell suspensions

, 2007
Results on the rheological behavior of novel CHO cell suspensions in a large range of concentrations are reported. The concentration dependent yield stress and elastic plateau modulus are formalized in the context of fractal aggregates under shear, and ...
Duperray, Alain, Iordan, Andreea, Verdier, Claude   +2 more
core   +2 more sources

Parametrical modeling and design optimization of blood plasma separation device with microchannel mechanism [PDF]

, 2009
This paper presents an analysis of biofluid behavior in a T-shaped microchannel device and a design optimization for improved biofluid performance in terms of particle liquid separation.
Bailey, Chris, Desmulliez, Marc P. Y., Kersaudy-Kerhoas, Maïwenn, Kersaudy-Kerhoas, Maïwenn, Patel, Mayur K., Xue, Xiangdong   +5 more
core   +1 more source