Results 41 to 50 of about 8,252,873 (160)

Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease

, 2017
Red blood cell (RBC) transfusions are of vital importance in patients with sickle cell disease (SCD). However, a major complication of transfusion therapy is alloimmunization.
Geissler, Judy, Pirenne, France, Kerkhoffs, Jean Louis H., Sins, Joep W. R., van Bruggen, Robin, Rijneveld, Anita W., Fijnvandraat, Karin, Kerkhoffs, Jean-Louis H., Kuijpers, Taco W., Pakdaman, Sadaf, Sins, Joep W.R., Nagelkerke, Sietse Q., Tanck, Michael W., Bruggeman, Christine, van den Berg, Timo K., Habibi, Anoosha, Biemond, Bart J., Meinderts, Sanne M.   +17 more
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EFFECTS OF CHEMOTHERAPY ON RED BLOOD CELL ALLOIMMUNIZATION IN CHILDREN [PDF]

, 2015
Background: Red cell transfusions can lead to alloimmunization; however, pediatric alloimmunization frequency has not been well studied, and it may vary among diagnostic subgroups. Subgroups such as pediatric hematology/oncology patients require numerous
SOLH, ZIAD
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The Diagnosis and Prenatal Management of Non‐RHD Alloimmunizations

Prenatal Diagnosis, EarlyView.
ABSTRACT Red blood cell (RBC) alloimmunization remains a relevant cause of hemolytic disease of the fetus and newborn (HDFN). Although RhD immunization has significantly decreased since the implementation of systematic prophylaxis, it is still the main cause of alloimmunization in pregnancy.
Mar Bennasar, Antoni Borrell
wiley   +1 more source

Frequency of Red Cell Alloimmunization in Patients with β-Major Thalassemia in an Iranian Referral Hospital

, 2008
Objective: Frequency of red cell alloimmunization in patients with β-major-thalassemia in Mofid children's hospital. Tehran. Iran Material & Methods: This is a cross-sectional descriptive study conducted in Mofid children's hospital, March 2007. A total
Taghi, Arzanian,Mohammad, Shamsian, Bibi Shahin, Alavi, Samin, Khojasteh, Omid, Shamshiri, Ahmad Reza   +4 more
core   +2 more sources

The Nlrp3 Inflammasome Does Not Regulate Alloimmunization to Transfused Red Blood Cells in Mice

EBioMedicine, 2016
Red blood cell (RBC) transfusions are essential for patients with hematological disorders and bone marrow failure syndromes. Despite ABO matching, RBC transfusions can lead to production of alloantibodies against “minor” blood group antigens.
David R. Gibb, Samuele Calabro, Dong Liu, Christopher A. Tormey, Steven L. Spitalnik, James C. Zimring, Jeanne E. Hendrickson, Eldad A. Hod, Stephanie C. Eisenbarth   +8 more
doaj   +1 more source

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

Transfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza, Thamy Caroline Silva, Mateus Domentino, Marina Cavalcanti Albuquerque Veiga Conrado, João Vitor Bernardo Oliveira, Felipe Augusto Rós, Caroline Gabe, Elyse Moritz, Akemi Chiba, Paula Villaça, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Dante Langhi, Carla Luana Dinardo   +14 more
wiley   +1 more source

Alloimmunization following red blood cell exchange in a patient with Rh(D) variant [PDF]

, 2019
A case report of an Rh(D) variant stem cell transplant recipient with sickle cell disease who developed anti-D alloimmunization following red blood cell exchange prior to stem cell transplantation.
Sally Campbell-Lee (10638875), Vladimir Vidanovic (10640717), Chelsea Sheppard (14671056), David Allison (9094295), David Loeffler (14671053), Lavinia Sereseanu (14671055), Santosh Saraf (10639763), Jason E. Crane (11615917)   +7 more
core   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

Investigating the molecular basis of the serological Rh D‐negative phenotype in Indonesia: nature, frequency, and impact for diagnostics

Transfusion, EarlyView.
Abstract Background Although widely studied and reported for more than 30 years, the molecular basis of Rh D‐negativity has remained unexplored in several regions of the world, including in Indonesia, Southeast Asia. Study Design and Methods A subset of 436 Indonesian blood donors originally typed D‐negative (D–) by routine serological testing was ...
Tonny Wongso, Teguh Triyono, Caroline Bénech, Gauthier Thomas, Sasi Widuri, Martono Adi Triyogo, Ni Kadek Mulyantari, Misnah Syarifuddin, Halimi Maksum, Winda Astuti Taruno, Hasna Fadlilatul Bidayah, Yann Fichou   +11 more
wiley   +1 more source

Red blood cell alloimmunization among recipients of blood transfusion in India

, 2022
Immunohematology: Red cell alloimmunization and strategies for its prevention. Background: There is a varied prevalence of red cell alloimmunization being reported from different parts of India.
Chenna, Deepika, Dr
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