Results 31 to 40 of about 199,216 (261)

Red Blood Cell Distribution Width: Another Prognostic Factor for COVID-19?

Clinical Hematology International, 2021
The coronavirus disease 2019 (COVID-19) is a pandemic with a high rate of hospitalization, admission to intensive care units, and mortality. Identifying patients at the highest risk for severe disease is important to facilitate early, aggressive ...
Maria Lagadinou, Despoina Gkentzi, Markos N. Marangos, Fotini Paliogianni, Elena E. Solomou   +4 more
doaj   +1 more source

Red Cell Distribution Width, Revisited [PDF]

Laboratory Medicine, 2013
The red blood cell distribution width (RDW), as part of an automated complete blood count (CBC), is a routinely available parameter on hematology analyzers. This parameter is the most commonly reported index of the variation in red cell volume and can be used to detect subtle degrees of anisocytosis.
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Red Cell Distribution Width and Acute Complications of Diabetes [PDF]

Acta Endocrinologica (Bucharest), 2018
Red cell distribution width (RDW) has been associated with type 2 diabetes (T2DM), however data in relation to diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar non-ketotic acidosis (HONK) remains unclear.The aim of this study was to evaluate the association between RDW, MCV, and RDW/MVC values and acute complications in T2DM.RDW was measured ...
Atalay, Hande, Boyuk, B., Ateş, Murat, Güzel, Savaş, Çelebi, A., Ekizoğlu, İsmail   +5 more
openaire   +3 more sources

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Association of Red Blood Cell Distribution Width with Stroke Prognosis Among Patients with Small Artery Occlusion: A Hospital-Based Prospective Follow-Up Study

International Journal of General Medicine, 2022
Yalin Guan,1,2,* Wenchao Zuo,1,2,* Kun Jia,1,2,* Changshen Yu,2 Feng Liu,2 Zhaoyang Lv,2 Dong Wang,3 Fu-Dong Shi,1 Xinping Wang2 1Department of Neurology, Tianjin Medical University General Hospital, Tianjin, 300052, People’s Republic of ...
Guan Y, Zuo W, Jia K, Yu C, Liu F, Lv Z, Wang D, Shi FD, Wang X   +8 more
doaj  

Association Between Red Blood Cell Distribution Width and Thyroid Function

Frontiers in Endocrinology, 2022
AimRed blood cell distribution width (RDW) is an important parameter with broad biological implications. However, the study investigating the association between RDW and thyroid function remains sparse and inconsistent.
Guowei Zhou, Yueqin Ai, Song Guo, Quan Chen, Xiao Feng, Kun Xu, Gaoyuan Wang, Chaoqun Ma   +7 more
doaj   +1 more source

Red blood cell distribution width and ischaemic stroke [PDF]

Stroke and Vascular Neurology, 2017
The red blood cell distribution width (RDW) is a measure of red blood cell (RBC) size heterogeneity, which is easily calculated by dividing the SD of erythrocyte volumes for the mean corpuscular volume. Recent reporter suggested that, besides haematological diseases and anaemia, many human disorders may be closely associated with the elevated RDW.
Feng, Gang-Hua, Li, Hai-Peng, Li, Qiu-Li, Fu, Ying, Huang, Ren-Bin   +4 more
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source