Results 101 to 110 of about 3,739,606 (279)

Estimating IUCN Red List population reduction: JARA—A decision‐support tool applied to pelagic sharks

open access: yesConservation Letters, 2019
The International Union for Conservation of Nature's (IUCN) Red List is the global standard for quantifying extinction risk but assessing population reduction (criterion A) of wide‐ranging, long‐lived marine taxa remains difficult and controversial.
R. Sherley   +10 more
semanticscholar   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Endangered Gladiolus Species of Turkey

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2019
Gladiolus is a perennial geophyte, semi-rustice herb and belongs to the Iridaceae family. Gladiolus is an important bulbous ornamental plant. It is used as cut flowers, garden and potted plants.
Sevim Demir, Fisun Gürsel Çelikel
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Mordovia State Nature Reserve's 80th anniversary

open access: yesNature Conservation Research: Заповедная наука, 2016
Brief physical-geographical characteristics, history of creation and development of the Mordovia State Nature Reserve territory are presented. We listed aims and objectives assigned for the Mordovia Reserve in different periods. During the first years of
Elena V. Vargot
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

All hands on deck: An innovative approach to sustained and sustainable conservation funding for endangered plants and ecosystems

open access: yesConservation Science and Practice, 2022
Lorenzo Gianguzzi   +3 more
doaj   +1 more source

Aufruf zur Mitarbeit [Roten Liste Nordrhein-Westfalen]

open access: yesArachnologische Mitteilungen, 1998
Diversa
Kreuels, Martin, Weiss, Ingmar
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy