Results 121 to 130 of about 3,023,691 (351)

Stranding of a whale shark, Rhincodon typus (Smith) at Pamban, Gulf of Mannar [PDF]

, 2008
The stranding of whale sharks in shallow waters along the Indian coast is not uncommon. Whale shark is listed as an endangered species as per the IUCN Red List (2000)
Boominathan, N, Gandhi, A, Ramamoorthy, N, Venkatesan, V   +3 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Red-Teaming NLW: A Top Ten List of Criticisms About Non-Lethal Weapons [PDF]

, 2015
Critics of non-lethal weapons (NL W) have asserted numerous complaints about the concepts, the Department of Defense research and development efforts, and the pace of innovation in the field.
Koplow, David A
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

An Announced Extinction: The Impacts of Mining on the Persistence of Arthrocereus glaziovii, a Microendemic Species of Campos Rupestres

Conservation
The mountaintops of eastern Brazil harbor the highest rates of plant endemism in South America. However, local biodiversity faces constant threats due to habitat loss and mining activities.
Patrícia de Abreu Moreira, Andrea Pires, Marina do Vale Beirão   +2 more
doaj   +1 more source

Charophytes (Charophyceae, Charales) of South Kazakhstan: Diversity, Distribution, and Tentative Red List. [PDF]

Plants (Basel), 2023
Nurashov S, Jumakhanova G, Barinova S, Romanov R, Sametova E, Jiyenbekov A, Shalgimbayeva S, Smith TE.   +7 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Identifying species likely threatened by international trade on the IUCN Red List can inform CITES trade measures. [PDF]

Nat Ecol Evol, 2023
Challender DWS, Cremona PJ, Malsch K, Robinson JE, Pavitt AT, Scott J, Hoffmann R, Joolia A, Oldfield TEE, Jenkins RKB, Conde DA, Hilton-Taylor C, Hoffmann M.   +12 more
europepmc   +1 more source

From red to green: achieving an environmental pact at the municipal level in Paragominas (Pará, Brazilian Amazon). [PDF]

, 2014
A Red List of Deforestation was published by Brazil?s federal government in 2008, listing 36 municipalities with the highest rates of deforestation in the Amazon as a policy measure to prioritize efforts to combat deforestation.
BARLOW, J., COUDEL, E., FERREIRA, J., GARDNER, T., PARRY, L., VIANA, C.   +5 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source