Results 51 to 60 of about 404,578 (305)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Confocal images of mixed hippocampal cultures immunostained with anti-P2Y receptors (green) and neuronal markers anti-MAP-2 (red)

, 2011
Both P2Y2 and P2Y4 receptor immunostaining is not seen in neuronal cell bodies or processes but astrocytes are profusely stained. In merged images, some pixels appear yellow because of the neurons (red) overlying the brightly stained (green) astrocytes ...
Preeti G. Joshi (49674), Gulnaz Begum (53576), Nanda B. Joshi (53577), Bhupesh Mehta (53575)   +3 more
core   +1 more source

APLICACIÓN DE REDES NEURONALES EN LA CLASIFICACIÓN DE ARCILLAS APLICAÇÃO DE REDES NEURONAIS NA CLASSIFICAÇÃO DE ARGILAS APPLICATION OF NEURAL NETWORKS IN CLASSIFICATION OF CLAYS

Revista EIA, 2012
Las arcillas son la materia prima fundamental en la fabricación de productos para el sector constructor tales como baldosas, enchapes, pavimentos y ladrillos.
Jairo Gómez, Jaime Sánchez, Aquiles Ocampo, José William Restrepo   +3 more
doaj  

ARQUITECTURA COMPUTACIONAL PARA PREDECIR EL RENDIMIENTO ACADÉMICO DE ALUMNOS DE LA UNIVERSIDAD AGOSTINHO NETO

Tecnología Educativa, 2016
El estudio de los factores que intervienen en el rendimiento académico de los alumnos ha sido y sigue siendo un tema objeto de investigación pedagógica por cuanto aporta información de mucho valor en el proceso de personalización de la enseñanza y en la
Pedro António Kinsumba, María Julia Becerra Alonso, Rogelio Lau Fernández   +2 more
doaj   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Diseño de una red neuronal convolucional para el reconocimiento facial [PDF]

, 2022
El presente trabajo de investigación muestra cómo se diseña una red neuronal convolucional para el reconocimiento de rostros. Para esto se necesitó generar una base de datos, la cual fue generada a partir de videos grabados por cada integrante.
Becerra Chávez, Richard Antonio, Surita Chasquero, Denis Iván, Rodríguez Farías, Luis Wenderley   +2 more
core  

Activity of Red Nucleus Neurons in the Cat during Postural Corrections [PDF]

The Journal of Neuroscience, 2010
The dorsal-side-up body posture in standing quadrupeds is maintained by the postural system, which includes spinal and supraspinal mechanisms driven by somatosensory inputs from the limbs. A number of descending tracts can transmit supraspinal commands for postural corrections. The first aim of this study was to understand whether the rubrospinal tract
Pavel V, Zelenin, Irina N, Beloozerova, Mikhail G, Sirota, Grigori N, Orlovsky, Tatiana G, Deliagina   +4 more
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Una mirada a la neurocomputación artificial

Revista de la Facultad de Medicina, 1998
Las Redes Neuronales Artificiales (RNA) son sistemas sintéticos que pueden emular una de las características propias de los seres humanos: la capacidad de memorizar y asociar hechos.
Jorge Eduardo Ortiz Triviño
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source