The HCDR3 sequences of the B-cell receptor (BCR) undergo constraints in length, amino acid use, and charge during maturation of B-cell precursors and after antigen encounter, leading to BCR and antibodies with high affinity to specific antigens.
Arancha Rodríguez-Caballero +31 more
doaj +1 more source
Direct Evidence from Spitzer for a low-luminosity AGN at the center of the Elliptical Galaxy NGC 315 [PDF]
We present the {\it Spitzer} Space Telescope InfraRed Array Camera (IRAC) and Multiband Imaging Photometer (MIPS) observations of the elliptical galaxy NGC 315.
G. G. Fazio +5 more
core +3 more sources
Movement Disorders in Childhood Thalamic Tumors
Investigators form St. Jude Children’s Research Hospital in Memphis, Tennessee analyzed movement disorder outcomes in patients with childhood thalamic tumors.
Rebecca Garcia-Sosa, Joanna Blackburn
doaj +1 more source
Extinction in the Coma of Comet 17P/Holmes [PDF]
On 2007 October 29 the outbursting comet 17P/Holmes passed within 0.79 arcsec of a background star. We recorded the event using optical, narrowband photometry and detect a 3% to 4% dip in stellar brightness bracketing the time of closest approach to the ...
Jewitt, David, Lacerda, Pedro
core +2 more sources
Extended Gas in Seyfert Galaxies: Near Infrared Observations of NGC 2110 and Circinus [PDF]
We present results of near--IR long-slit spectroscopy in the J and K bands of the Seyfert 2 galaxies NGC 2110 and Circinus, investigating the gaseous distribution, excitation, reddening and kinematics.
Storchi-Bergmann, T. +3 more
core +2 more sources
Diffusion Kurtosis Imaging for Detection of Early Brain Changes in Parkinson's Disease
We aimed to evaluate microscale changes in the bilateral red nucleus and substantia nigra of patients with Parkinson's disease (PD) using diffusion kurtosis imaging (DKI).
Jitian Guan +17 more
doaj +1 more source
Longitudinal Optogenetic Motor Mapping Revealed Structural and Functional Impairments and Enhanced Corticorubral Projection after Contusive Spinal Cord Injury in Mice [PDF]
Current evaluation of impairment and repair after spinal cord injury (SCI) is largely dependent on behavioral assessment and histological analysis of injured tissue and pathways. Here, we evaluated whether transcranial optogenetic mapping of motor cortex
Chai, Zhi +5 more
core +1 more source
Functional Specialization Within the Cat Red Nucleus [PDF]
Magnocellular (RNm) and parvicellular (RNp) divisions of the cat red nucleus (RN) project to the cervical spinal cord. RNp projects more heavily to upper cervical levels and RNm projects more heavily to lower levels. The cells in RN are active during reaching and grasping, and the differences in termination suggest that the divisions influence ...
K M, Horn +4 more
openaire +2 more sources
Somatosensory Stimulation With XNKQ Acupuncture Modulates Functional Connectivity of Motor Areas
Xingnao Kaiqiao (XNKQ) acupuncture is an acupuncture technique used for stroke patients. In 24 healthy volunteers, we applied this complex acupuncture intervention, which consists of a manual needle-stimulation on five acupuncture points (DU26 ...
Till Nierhaus +11 more
doaj +1 more source
SARS-CoV-2 Infection Triggers Auto-Immune Response in ARDS
Acute respiratory distress syndrome (ARDS) is a severe pulmonary disease, which is one of the major complications in COVID-19 patients. Dysregulation of the immune system and imbalances in cytokine release and immune cell activation are involved in SARS ...
Pablo Juanes-Velasco +19 more
doaj +1 more source

