Results 111 to 120 of about 257,904 (307)
, 2015 The Red Sea experiences strong atmospheric forcing through both wind stress and air–sea buoyancy fluxes. Direct observations and modeling experiment show a robust response that consists of a strong and complicated three-dimensional circulation pattern ...
Sarantis Sofianos +3 more
core +1 more source
Evaluation of downwelling diffuse attenuation coefficient algorithms in the Red Sea
, 2016 Despite the importance of the optical properties such as the downwelling diffuse attenuation coefficient for characterizing the upper water column, until recently no in situ optical measurements were published for the Red Sea. Kirby et al.
Jones, Burton +2 more
core +1 more source
Metagenomic covariation along densely sampled environmental gradients in the Red Sea
, 2017 Oceanic microbial diversity covaries with physicochemical parameters. Temperature, for example, explains approximately half of global variation in surface taxonomic abundance.
Stingl, Ulrich +7 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Ongoing decline of shark populations in the Eastern Red Sea
, 2016 Information on the abundance and diversity of Red Sea elasmobranchs is notoriously scarce, even though sharks are among the most profitable fisheries of the region. Effective conservation would ideally entail baselines on pristine conditions, yet no such
Berumen, Michael L. +2 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
An Optical Algorithm to Estimate Downwelling Diffuse Attenuation Coefficient in the Red Sea
, 2018 An optical algorithm is developed for the retrieval of the downwelling diffuse attenuation coefficient K (490) in the Red Sea using a comprehensive hydrolight simulated data set (N = 5000). We found a robust relationship between the K (490) and the ratio
Sarma, Yellepeddi V. B. +4 more
core +1 more source