Results 101 to 110 of about 2,373,679 (282)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Symmetric Responses to Diet by Plumage Carotenoids in Violet-Sensitive Piciform–Coraciiform Birds

open access: yesDiversity
Biological studies on symmetry can be expanded to consider red (longer wavelengths) and blue (shorter wavelengths) shifts as antisymmetries (opposite-pattern symmetries), which may arise from similar underlying causes (invariant process symmetries).
Robert Bleiweiss
doaj   +1 more source

Experimental Characterization of In Silico Red-Shift-Predicted iLOVL470T/Q489K and iLOVV392K/F410V/A426S Mutants. [PDF]

open access: yesACS Omega, 2022
Wehler P   +5 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Infra-Red Frequency Shifts [PDF]

open access: yesNature, 1960
THE effect of liquefaction and solution in different solvents on infra-red group frequencies has previously been considered in terms of changes in dielectric constant and postulated local association effects (for example, Caldow and Thompson1, and Bellamy and Williams2).
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Protonation states of highly conserved carboxylic acids in NeoR

open access: yesBiophysics and Physicobiology
Neorhodopsin (NeoR), an enzymerhodopsin, has unique molecular properties. NeoR absorbs near-infrared light whose λmax is located at 690–700 nm. Upon light absorption, NeoR is photoisomerized into the 7-cis form with low quantum yield. Unique color-tuning
Ritsu Mizutori   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The Solar Red-Shift [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1960
Shortly after Rowland's fundamental study of the wavelengths of Fraunhofer lines, Jewell in 1896 observed that the solar wavelengths were shifted to the red side of the corresponding wavelengths observed in the laboratory. This shift became known as the red shift of solar lines, and at first led to various erroneous concepts of conditions in the solar ...
openaire   +1 more source

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