Results 131 to 140 of about 743,057 (300)

High sensitive fast gamma radiation sensor based on Yb-doped optical fiber: offline and online detection

open access: yesJPhys Photonics
Radiation science has a wide range of applications, from industrial uses and medical treatments to space research and national defense. Optical fiber technology offers a flexible and sensitive alternative solution for accurate radiation measurements in ...
Esra Kendir Tekgül   +3 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Demography of deep-dwelling red coral (Corallium rubrum) populations

open access: yes, 2013
Mediterranean red coral (Corallium rubrum, L 1758, Octocorallia, Gorgonacea) is a colonial anthozoan endemic to the Mediterranean Sea. Due to the high economic value of its carbonate axial skeleton this species has been harvested and traded for more than
PRIORI, CRISTINA
core  

Structural Analysis of the Large Stokes Shift Red Fluorescent Protein tKeima

open access: yesMolecules
The Keima family comprises large Stokes shift fluorescent proteins that are useful for dual-color fluorescence cross-correlation spectroscopy and multicolor imaging.
Ki Hyun Nam, Yongbin Xu
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Sleep Disruption and Shift Work Associate with Increased Risk of Reproductive Endocrine Disorders: Evidence from UK Biobank and Mendelian Randomization

open access: yesInternational Journal of Women's Health
Hanke Zhang,* Ruyu Luo,* Yuqing Fang, Hongbo Wang, Yanhui Li* Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, People’s Republic ...
Zhang H, Luo R, Fang Y, Wang H, Li Y
doaj  

Home - About - Disclaimer - Privacy