Results 121 to 130 of about 3,297,358 (361)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Minería de datos en redes sociales por medio de un correlacionador de datos [PDF]

open access: yes, 2017
Twitter is a social network that has gained great importance as a mean of communication. There are millions of users who use this social network to learn about different topics of their interest.
Álvarez Espín, Christian Alexis
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Nuevas tendencias en el proceso de formación y mentoría de profesores universitarios noveles en su primer año de docencia

open access: yesOlhar de Professor, 2013
En el presente artículo se describe el programa de iniciación a la docencia de la Universidad de Sevilla a partir de la propia vivencia y se proponen líneas de mejora a cada una de sus fases, entre otras: crear y dinamizar una red social donde profesores
Carmen Yot Domínguez   +1 more
doaj  

Economía social y agricultura familiar : hacia la construcción de nuevos paradigmas de intervención [PDF]

open access: yes, 2010
465 p. ; 15x21 cm.Libro ElectrónicoLa publicación se inscribe en el marco de una estrategia de desarrollo rural con enfoque territorial propiciada por el INTA y en sus más de 400 páginas se analiza a fondo la economía social y se relatan interesantes ...
Caballero, Luis (Comp.)   +3 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Comments on Caddo Origins in Northwest Louisiana [PDF]

open access: yes, 2009
This paper presents some of my thoughts on the issue of Caddo origins from the perspective of the Red River drainage in northwest Louisiana. These ideas were assembled prior to the Caddo discussion group meeting held in December 2008 and have been only ...
Girard, Jeffery S.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Effects of Genetics and Environment on Red Flour Beetle Aggregation [PDF]

open access: yes, 2018
Red Flour Beetles are major pests for farmers storing grain and cause large profit losses. These beetles infest grain stores and their presence leads to mold growth (Baldwin).
Marshall, Jeremy, Toothaker, J. E.
core  

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