Results 131 to 140 of about 407,327 (266)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Enhanced graph coevolution network for social network analysis using assimilation modified emotional algorithm. [PDF]

Sci Rep
Li HH, Chang PC, Liao YH.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

The impact of state and trait general and social anxiety on theory of mind. [PDF]

Sci Rep
Foulds C, Khudiakova V, Surtees ADR.
europepmc   +1 more source

Red social privada y segura

, 2020
Debido al creciente auge del uso de redes sociales y, por tanto, también de la sensibilidad respecto a la privacidad de los usuarios, la privacidad y seguridad de estas se ha convertido en un tema de gran relevancia en la actualidad. El proyecto consistirá en el análisis de varias redes sociales en términos de privacidad, seguridad y funcionalidad con ...
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Diálogos terapéuticos en la red social. Jaakko Seikkula y Tom Erik Arnkil. Barcelona: Editorial Herder, 2016, 312 pp.

Trabajo Social, 2020
Bárbara Zapata Cadavid
doaj   +1 more source

At-Home Red Light Therapy Devices: Promotion and Recommendation Patterns on Social Media in the Context of Limited Evidence. [PDF]

Cureus
Merkle T, Tomczak L, Do K, Aji M, Ilyas E.   +4 more
europepmc   +1 more source

Red social de eventos PLANBOO

, 2016
El proyecto consiste en una red social, de nombre PLANBOO, donde se presentan y recomiendan al usuario lugares o eventos de acuerdo a los gustos del mismo, igualmente se permitirá que los interesados manejen agendas donde podrán agregar los planes que seleccionen -- El proyecto está entendido como un modelo de negocio a futuro, por lo cual no se ha ...
Arango Arboleda, Víctor Hugo, Ríos Jaramillo, Carlos Andrés   +1 more
openaire   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source