Results 91 to 100 of about 8,060 (258)
Facebook: rede social educativa?
, 2010 Actualmente, as redes sociais fazem parte da vida dos nossos alunos. O Facebook é, provavelmente, o principal sítio de encontro, comunicação, partilha e interacção de ideias e assuntos de interesse comum, entre os estudantes universitários. Neste contexto e dadas as possibilidades que as redes sociais oferecem para a criação de um ambiente de ...
Patrício, Maria Raquel +1 more
openaire +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Diálogos, 2017 Dissertação de mestrado defendida no Programa Associado de Pós-Graduação em História UEM/UEL, em 28 de março de 2003, sob orientação da Profª.Dra. Hilda Pívaro Stadniky (UEM) e examinada por banca constituída pelas professoras doutoras Ana Silvia Volpi ...
Claudia Priori
doaj
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
, 2018 Diseño y ejecución del libro "redes sociales": ilustraciones, portada, texto y maquetación del mismo. El objetivo principal del libro es reflejar la cultura popular de la actualidad que vemos en las redes sociales y conservar esos momentos en el ...
openaire +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Em Questão, 2011 O trabalho busca apresentar uma reflexão de como a rede social dos social games é constituída a partir de uma discussão referente aos mecanismos de difusão de informações do jogo.
Rebeca Recuero Rebs +1 more
doaj
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source