Results 71 to 80 of about 688,031 (301)

Flavins Act as a Critical Liaison Between Metabolic Homeostasis and Oxidative Stress in the Retina

Frontiers in Cell and Developmental Biology, 2020
Derivatives of the vitamin riboflavin, FAD and FMN, are essential cofactors in a multitude of bio-energetic reactions, indispensable for lipid metabolism and also are requisites in mitigating oxidative stress.
Tirthankar Sinha, Muna I. Naash, Muayyad R. Al-Ubaidi   +2 more
doaj   +1 more source

Electron tunneling between two electrodes mediated by a molecular wire containing a redox center

, 2009
We derive an explicit expression for the quantum conductivity of a molecular wire containing a redox center, which is embedded in an electrochemical environment. The redox center interacts with the solvent, and the average over the solvent configurations
A.K. Mishra, A.V.B. Cruz, Adams, Albrecht, Albrecht, Alessandrini, Alexandrov, Alexandrov, Amlani, Brandbyge, Camalet, Camalet, Caroli, Chi, Cygan, Damle, Davis, Decher, DiVentra, Evenson, Flensberg, Galperin, Han, He, Holmin, Hu, Jauho, Kummamuru, Kuznetsov, Kuznetsov, Kuznetsov, Lent, Li, Lieberman, Lundin, McConnell, Meir, Mozyrsky, Mujica, Mujica, Mujica, Newton, Schmickler, Schmickler, Schmickler, Schmickler, Segal, Sen, Siddharth, Tao, Taylor, Taylor, Tian, Tran, W. Schmickler, Wingreen, Xiao, Zhu   +57 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Investigating Mitochondrial Redox Potential with Redox-sensitive Green Fluorescent Protein Indicators [PDF]

Journal of Biological Chemistry, 2004
Current methods for determining ambient redox potential in cells are labor-intensive and generally require destruction of tissue. This precludes single cell or real time studies of changes in redox poise that result from metabolic processes or environmental influences.
George T, Hanson, Robert, Aggeler, Devin, Oglesbee, Mark, Cannon, Roderick A, Capaldi, Roger Y, Tsien, S James, Remington   +6 more
openaire   +2 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Propriedades redox e grupos funcionais de ácidos húmicos isolados de adubos orgânicos Redox properties and functional groups of humic acids isolated from organic residues

Revista Brasileira de Ciência do Solo, 2007
Dependendo das condições do sistema, os ácidos húmicos podem atuar como oxidantes ou redutores. Nos sistemas naturais, o fluxo de elétrons está diretamente associado à quantidade e à qualidade do húmus.
Marihus Altoé Baldotto, Luciano Pasqualoto Canellas, Maria Cristina Canela, Marcelo Luiz Simões, Ladislau Martin-Neto, Maurício Paulo Ferreira Fontes, Ary Carlos Xavier Velloso   +6 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

The redox potential interferes with the expression of laminin binding molecules in Bacteroides fragilis

Memorias do Instituto Oswaldo Cruz, 2008
The Bacteroides fragilis ATCC strain was grown in a synthetic media with contrasting redox potential (Eh) levels [reduced (-60 mV) or oxidised (+100mV)] and their adhesion capacity to extracellular matrix components was evaluated.
Eliane de Oliveira Ferreira, Edwin Alexander Yates, Morris Goldner, Rossiane Cláudia Vommaro, Fernando Costa e Silva Filho, Débora Barreiros Petrópolis, Regina MC Pilotto Domingues   +6 more
doaj   +1 more source

Characterisation of components and mechanisms involved in redox-regulation of protein import into chloroplasts [PDF]

, 2009
The vast majority of chloroplast proteins is encoded in the nucleus and thus has to be posttranslationally imported into the organelle, a process that is facilitated by two multimeric protein machineries, the Toc and Tic complexes (translocon at the ...
Stengel, Anna
core  

Reversible Anionic Redox Activities in Conventional LiNi1/3 Co1/3 Mn1/3 O2 Cathodes. [PDF]

, 2020
Redox reactions of oxygen have been considered critical in controlling the electrochemical properties of lithium-excessive layered-oxide electrodes. However, conventional electrode materials without overlithiation remain the most practical.
Cho, Kyeongjae, Cho, Maenghyo, Kang, Yong-Mook, Kim, Duho, Lee, Gi-Hyeok, Wu, Jinpeng, Yang, Wanli   +6 more
core