Results 131 to 140 of about 6,124,322 (291)
An improved reduced-order model for pressure drop across arterial stenoses. [PDF]
PLoS One, 2021 Lyras KG, Lee J.
europepmc +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
A reduced-order model of the spine to study pediatric scoliosis. [PDF]
Biomech Model Mechanobiol, 2021 Neelakantan S, Purohit PK, Pasha S.
europepmc +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Numerical Prediction of Two-Phase Flow through a Tube Bundle Based on Reduced-Order Model and a Void Fraction Correlation. [PDF]
Entropy (Basel), 2021 Dubot C +5 more
europepmc +1 more source
Koopman Reduced-Order Modeling with Confidence Bounds
SIAM Journal on Applied Dynamical SystemsThis paper introduces a reduced order modeling technique based on Koopman operator theory that gives confidence bounds on the model's predictions. It is based on a data-driven spectral decomposition of the Koopman operator. The reduced order model is constructed using a finite number of Koopman eigenvalues and modes, while the rest of spectrum is ...
Mohr, Ryan +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Development of a Reduced Order Model for Turbine Blade Cooling Design
International Journal of Turbomachinery, Propulsion and PowerRotating detonation engines (RDEs) are expected to have higher specific work and efficiency, but the high-temperature transonic flow delivered by the combustor poses relevant design and technological difficulties.
Andrea Pinardi +2 more
doaj +1 more source
A Data-Driven Space-Time-Parameter Reduced-Order Model with Manifold Learning for Coupled Problems: Application to Deformable Capsules Flowing in Microchannels. [PDF]
Entropy (Basel), 2021 Boubehziz T +5 more
europepmc +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source