Results 131 to 140 of about 26,791,362 (287)
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
, 2019 This study develops a reduced-order power plant dispatch model and uses it to simulate marginal emissions factors (MEFs) for the 2014–2017 United States (U.S.) electric grid at the North American Electric Reliability Corporation (NERC) regional level ...
Thomas A. Deetjen (7301129) +3 more
core +1 more source
Development of Reduced Order Model for Steady State Flow Field in Two-dimensional Lower Plenum
Yuanzineng kexue jishuIn the field of reactor thermal-hydraulics, system thermal-hydraulic codes have been widely employed to quickly determine the global response characteristics of the primary system.
SHANG He1, PENG Minjun1, 2, XIA Genglei1, 2, , ZHANG Shiqi1, ZHU Shijie1
doaj +1 more source
Semi-mechanistic reduced order model of pharmaceutical tablet dissolution for enabling Industry 4.0 manufacturing systems. [PDF]
Int J Pharm, 2023 Ferdoush S, Gonzalez M.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Generative design of graded metamaterial arrays for dynamic response modulation
Materials & DesignMechanical metamaterials (MMs) are micro-structured systems that have long attracted research as well as application interests due to their exotic dynamic functionalities and properties not seen in ordinary materials.
Weidi Wang +2 more
doaj +1 more source
A reduced-order model of the spine to study pediatric scoliosis. [PDF]
Biomech Model Mechanobiol, 2021 Neelakantan S, Purohit PK, Pasha S.
europepmc +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
An improved reduced-order model for pressure drop across arterial stenoses. [PDF]
PLoS One, 2021 Lyras KG, Lee J.
europepmc +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source