Results 71 to 80 of about 6,124,322 (291)

Moment Matching Based Model Reduction for LPV State-Space Models

open access: yes, 2015
We present a novel algorithm for reducing the state dimension, i.e. order, of linear parameter varying (LPV) discrete-time state-space (SS) models with affine dependence on the scheduling variable.
Bastug, Mert   +5 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Evolve Filter Stabilization Reduced-Order Model for Stochastic Burgers Equation

open access: yesFluids, 2018
In this paper, we introduce the evolve-then-filter (EF) regularization method for reduced order modeling of convection-dominated stochastic systems. The standard Galerkin projection reduced order model (G-ROM) yield numerical oscillations in a convection-
Xuping Xie   +2 more
doaj   +1 more source

Reduced-order modeling of soft robots

open access: yesPLOS ONE, 2018
We present a general strategy for the modeling and simulation-based control of soft robots. Although the presented methodology is completely general, we restrict ourselves to the analysis of a model robot made of hyperelastic materials and actuated by cables or tendons. To comply with the stringent real-time constraints imposed by control algorithms, a
Chenevier, Jean   +4 more
openaire   +8 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Progressive construction of a parametric reduced-order model for PDE-constrained optimization [PDF]

open access: yes, 2014
An adaptive approach to using reduced-order models as surrogates in PDE-constrained optimization is introduced that breaks the traditional offline-online framework of model order reduction.
Farhat, Charbel, Zahr, Matthew J.
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Reduced order models based on pod method for schrödinger equations

open access: yesMathematical Modelling and Analysis, 2013
Reduced-order models (ROM) are developed using the proper orthogonal decomposition (POD) for one dimensional linear and nonlinear Schrödinger equations. The main aim of this paper is to study the accuracy and robustness of the ROM approximations.
Gerda Jankevičiutė   +3 more
doaj   +1 more source

An orifice shape-based reduced order model of patient-specific mitral valve regurgitation

open access: yesEngineering Applications of Computational Fluid Mechanics, 2021
Mitral valve regurgitation (MR) is one of the most prevalent valvular heart diseases. Its quantitative assessment is challenging but crucial for treatment decisions.
J. Franz   +12 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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