Results 51 to 60 of about 1,843,340 (266)
Estimating flow fields with reduced order models
Heliyon, 2023 The estimation of fluid flows inside a centrifugal pump in realtime is a challenging task that cannot be achieved with long-established methods like CFD due to their computational demands. We use a projection-based reduced order model (ROM) instead.
Kamil David Sommer +4 more
openaire +4 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Reduced-order modeling for Ablowitz–Ladik equation
Mathematics and Computers in Simulation, 2023 In this paper, reduced-order models (ROMs) are constructed for the Ablowitz-Ladik equation (ALE), an integrable semi-discretization of the nonlinear Schrödinger equation (NLSE) with and without damping. Both ALEs are non-canonical conservative and dissipative Hamiltonian systems with the Poisson matrix depending quadratically on the state variables ...
Murat Uzunca, Bülent Karasözen
openaire +4 more sources
Multi-Frequency Aeroelastic ROM for Transonic Compressors
AerospaceThe accurate prediction of the aeroelastic behavior of turbomachinery for aircraft propulsion poses a difficult yet fundamental challenge, since modern aircraft engines tend to adopt increasingly slender blades to achieve a higher aerodynamic efficiency,
Marco Casoni +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A turbulence reduced order model based on non-interpolated convolutional autoencoder
Xibei Gongye Daxue XuebaoReduced-order modeling stands as a pivotal method in curbing the computational expenses linked with expansive fluid dynamics quandaries by employing proxy numerical simulations.
WU Pin, ZHANG Bo, SONG Chao, ZHOU Zhu
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A reduced order model to assist welding parameter setup
Mechanics & IndustryThis article demonstrates the time saving in industrial process setup using numerical reduced order modelling (ROM). The numerical simulations may supply useful information to design manufacturing processes but are often time consuming and then not ...
Le Guennec Yves, Morville Simon
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source