Results 61 to 70 of about 26,791,362 (287)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Dissipativity preserving model reduction by retention of trajectories of minimal dissipation [PDF]
, 2009 We present a method for model reduction based on ideas from the behavioral theory of dissipative systems, in which the reduced order model is required to reproduce a subset of the set of trajectories of minimal dissipation of the original system.
Paolo Rapisarda +9 more
core +1 more source
Multi-Frequency Aeroelastic ROM for Transonic Compressors
AerospaceThe accurate prediction of the aeroelastic behavior of turbomachinery for aircraft propulsion poses a difficult yet fundamental challenge, since modern aircraft engines tend to adopt increasingly slender blades to achieve a higher aerodynamic efficiency,
Marco Casoni +2 more
doaj +1 more source
Reduced-Order Modeling of the Fluidic Pinball [PDF]
, 2019 The fluidic pinball is a geometrically simple flow configuration with three rotating cylinders on the vertex of an equilateral triangle. Yet, it remains physically rich enough to host a range of interacting frequencies and to allow testing of control laws within minutes on a laptop.
Pastur, Luc +3 more
openaire +4 more sources
Reduced-order modeling for Ablowitz–Ladik equation
Mathematics and Computers in Simulation, 2023 In this paper, reduced-order models (ROMs) are constructed for the Ablowitz-Ladik equation (ALE), an integrable semi-discretization of the nonlinear Schrödinger equation (NLSE) with and without damping. Both ALEs are non-canonical conservative and dissipative Hamiltonian systems with the Poisson matrix depending quadratically on the state variables ...
Murat Uzunca, Bülent Karasözen
openaire +5 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Ctene kinematics vs. reduced-order model approximation.
, 2023 This video shows a side-to-side comparison of a ctenophore rowing and the reduced-order model approximation. (MP4)
Adrian Herrera-Amaya (17409977) +1 more
core +1 more source
A turbulence reduced order model based on non-interpolated convolutional autoencoder
Xibei Gongye Daxue XuebaoReduced-order modeling stands as a pivotal method in curbing the computational expenses linked with expansive fluid dynamics quandaries by employing proxy numerical simulations.
WU Pin, ZHANG Bo, SONG Chao, ZHOU Zhu
doaj +1 more source
A Reduced Order Model for Monitoring Aeroengines Condition in Real Time
Aerospace, 2023 A very fast reduced order model is developed to monitor aeroengines condition (defining their degradation from a baseline state) in real time, by using synthetic data collected in specific sensors.
Jose Rodrigo +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source