Results 111 to 120 of about 7,720,158 (325)

Autoencoders for discovering manifold dimension and coordinates in data from complex dynamical systems

open access: yesMachine Learning: Science and Technology
While many phenomena in physics and engineering are formally high-dimensional, their long-time dynamics often live on a lower-dimensional manifold. The present work introduces an autoencoder framework that combines implicit regularization with internal ...
Kevin Zeng   +3 more
doaj   +1 more source

On the Selection of Tuning Methodology of FOPID Controllers for the Control of Higher Order Processes [PDF]

open access: yes, 2012
In this paper, a comparative study is done on the time and frequency domain tuning strategies for fractional order (FO) PID controllers to handle higher order processes. A new fractional order template for reduced parameter modeling of stable minimum/non-
Alomoush   +56 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Controlling quantum many-body systems using reduced-order modeling

open access: yesPhysical Review Research
Quantum many-body control is among the most challenging problems in quantum science due to its outstanding computational complexity in a general case. We propose an efficient approach to a class of many-body quantum control problems, where time-dependent
I. A. Luchnikov   +2 more
doaj   +1 more source

Reduced order modeling of fluid flows: Machine learning, Kolmogorov barrier, closure modeling, and partitioning

open access: yes, 2020
In this paper, we put forth a long short-term memory (LSTM) nudging framework for the enhancement of reduced order models (ROMs) of fluid flows utilizing noisy measurements. We build on the fact that in a realistic application, there are uncertainties in
Ahmed, Shady   +3 more
core  

The ROMES method for statistical modeling of reduced-order-model error [PDF]

open access: yes, 2014
This work presents a technique for statistically modeling errors introduced by reduced-order models. The method employs Gaussian-process regression to construct a mapping from a small number of computationally inexpensive `error indicators' to a ...
Carlberg, Kevin, Drohmann, Martin
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Reduced Order Modeling and Sliding Mode Control of Active Magnetic Bearing

open access: yesIEEE Access, 2019
Due to the accelerated growth in the field of power electronics and controller design techniques, the usage of the active magnetic bearing has picked up in industries. Active magnetic bearing helps the rotor to rotate freely without any physical contact.
Sudipta Saha   +3 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy