Results 81 to 90 of about 14,700,185 (245)

Exploring Advectable Latent Representations for Droplet Size Distributions With Physics‐Informed Autoencoders

open access: yesJournal of Advances in Modeling Earth Systems
Investigating the role of clouds and precipitation in the Earth system necessitates microphysical schemes capable of accurately describing the evolution of hydrometeor particle size distribution (PSD), while maintaining low computational costs ...
Kang‐En Huang   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

LiCROM: Linear-Subspace Continuous Reduced Order Modeling with Neural Fields [PDF]

open access: yes, 2023
Linear reduced-order modeling (ROM) simplifies complex simulations by approximating the behavior of a system using a simplified kinematic representation.
Grinspun, Eitan   +5 more
core  

Autoencoders for discovering manifold dimension and coordinates in data from complex dynamical systems

open access: yesMachine Learning: Science and Technology
While many phenomena in physics and engineering are formally high-dimensional, their long-time dynamics often live on a lower-dimensional manifold. The present work introduces an autoencoder framework that combines implicit regularization with internal ...
Kevin Zeng   +3 more
doaj   +1 more source

Neuro-Fuzzy Network-Based Reduced-Order Modeling of Transonic Aileron Buzz

open access: yesAerospace, 2020
In the present work, a reduced-order modeling (ROM) framework based on a recurrent neuro-fuzzy model (NFM) that is serial connected with a multilayer perceptron (MLP) neural network is applied for the computation of transonic aileron buzz.
Rebecca Zahn, Christian Breitsamter
doaj   +1 more source

KROM: Kernelized Reduced Order Modeling

open access: yesCoRR
We propose KROM, a kernel-based reduced-order framework for fast solution of nonlinear partial differential equations. KROM formulates PDE solution as a minimum-norm (Gaussian-process) recovery problem in an RKHS, and accelerates the resulting kernel solves by sparsifying the precision matrix via sparse Cholesky factorization.
Aras Bacho, Jonghyeon Lee, Houman Owhadi
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Applications of Reduced Order and Surrogate Modeling in Structural Dynamics

open access: yes, 2019
Despite recent advances in computational science, the adoption of computationally intensive, high-fidelity simulation models remains a challenge for many structural dynamics applications, especially those within the domain of uncertainty quantification ...
Alexandros A. Taflanidis   +5 more
core   +1 more source

Reduced order modeling for physically-based augmented reality [PDF]

open access: yes, 2018
International audienceIn this work we explore the possibilities of reduced order modeling for augmented reality applications. We consider parametric reduced order models based upon separate (affine) parametric dependence so as to speedup the associated ...
Chinesta, Francisco   +5 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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