Results 1 to 10 of about 648,387 (311)

Alcoholic liver cirrhosis, more than a simple hepatic disease – A brief review of the risk factors associated with alcohol abuse [PDF]

Journal of Mind and Medical Sciences, 2019
Liver cirrhosis is a significant public health problem, being an important cause of mortality and morbidity, responsible for approximately 1.8% of the total number of deaths in Europe.
Sergiu Ioan Micu, Madalina Elena Manea, Roxana Popoiag, Dragana Nikolic, Dumitru Andrada, Angelo Maria Patti, Marilena Musat, Cristian Balalau, Anca Rogoveanu, Manfredi Rizzo, Anca Pantea Stoian   +10 more
doaj   +2 more sources

Reduced Alcohol Consumption and Major Adverse Cardiovascular Events Among Individuals With Previously High Alcohol Consumption.

JAMA Netw Open
ImportanceCardiovascular benefits of mild to moderate alcohol consumption need to be validated in the context of behavioral changes. The benefits of reduced alcohol consumption among people who drink heavily across different subtypes of cardiovascular disease (CVD) are unclear.ObjectiveTo investigate the association between reduced alcohol consumption ...
Kang DO, Lee DI, Roh SY, Na JO, Choi CU, Kim JW, Kim EJ, Rha SW, Park CG, Kim YS, Kim Y, You HS, Kang HT, Jo E, Kim J, Lee JW, Jung JM.   +16 more
europepmc   +3 more sources

Risk of All-Cause Mortality in Alcohol-Dependent Individuals: A Systematic Literature Review and Meta-Analysis [PDF]

EBioMedicine, 2015
Background: Alcohol dependence (AD) carries a high mortality burden, which may be mitigated by reduced alcohol consumption. We conducted a systematic literature review and meta-analysis investigating the risk of all-cause mortality in alcohol-dependent ...
Philippe Laramée, Saoirse Leonard, Amy Buchanan-Hughes, Samantha Warnakula, Jean-Bernard Daeppen, Jürgen Rehm   +5 more
doaj   +3 more sources

Effects of an amino acid mixture on alcohol metabolism and alcohol-related symptoms in healthy adults [PDF]

Scientific Reports
Alcohol consumption is associated with metabolic burden and a range of alcohol-related symptoms. Amino acids have been suggested to support hepatic metabolism and recovery following alcohol consumption. This study investigated the effects of Amino Liver (
Hyeongyeong Kim, Hyung Joo Suh, Kisoo Han, Nari Kim, Eun Young Jung, Joon Young Shim   +5 more
doaj   +2 more sources

Social Threat Reduces Alcohol Consumption among College Students [PDF]

Alcohol and Alcoholism, 2022
Abstract Aims Past research suggests that people report a greater desire to consume alcohol when they experience social threat—or threats to their social selves, such as social exclusion. Nevertheless, experimental research on the role of social threat in alcohol consumption is limited.
Jacqueline Hua, Angela E Johnson, Sofia Pino, David Olson, Tony Nguyen, Lacye Lawson, Brendan Bedolla, Jennifer L Howell   +7 more
openaire   +2 more sources

Which drinkers have changed their alcohol consumption due to energy content concerns? An Australian survey

BMC Public Health, 2022
Background Alcohol is a discretionary, energy dense, dietary component. Compared to non-drinkers, people who consume alcohol report higher total energy intake and may be at increased risk of weight gain, overweight, and obesity, which are key preventable
Jacqueline Bowden, Nathan J. Harrison, Joanna Caruso, Robin Room, Simone Pettigrew, Ian Olver, Caroline Miller   +6 more
doaj   +1 more source

Global evidence of environmental and lifestyle effects on medical expenditures across 154 countries

Preventive Medicine Reports, 2022
Increases of health care expenditures (HCEs) challenge the financial capacity of governments and bring into question the quality of health care services in each country. It is known that modifiable risk factors (e.g.
Álex Escolà-Gascón, Josep Lluís Micó-Sanz, Andreu Casero-Ripollés   +2 more
doaj   +1 more source

Reduced alcohol consumption in mice lacking preprodynorphin [PDF]

Alcohol, 2006
Many studies suggest a role for endogenous opioid peptides and their receptors in regulation of ethanol intake. It is commonly accepted that the kappa-opioid receptors and their endogenous ligands, dynorphins, produce a dysphoric state and therefore may be responsible for avoidance of alcohol. We used mutant mice lacking preprodynorphin in a variety of
Yuri A, Blednov, Danielle, Walker, Marni, Martinez, R Adron, Harris   +3 more
openaire   +2 more sources

Reduced Contextual Discrimination following Alcohol Consumption or MDMA Administration in Mice. [PDF]

PLoS ONE, 2015
The recreational drugs, alcohol and 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy") have both been shown to cause immune activation in vivo, and they are linked to cognitive impairment and anxiety-like behaviors in rodents.
Emily M Johansson, María S García-Gutiérrez, María Moscoso-Castro, Jorge Manzanares, Olga Valverde   +4 more
doaj   +1 more source

M1 muscarinic receptor activation decreases alcohol consumption via a reduction in consummatory behavior

Pharmacology Research & Perspectives, 2022
Muscarinic acetylcholine receptors (mAChRs) have been shown to mediate alcohol consumption and seeking. Both M4 and M5 mAChRs have been highlighted as potential novel treatment targets for alcohol use disorders (AUD).
Leigh C. Walker, Erin J. Campbell, Kate L. Huckstep, Nicola A. Chen, Christopher J. Langmead, Andrew J. Lawrence   +5 more
doaj   +1 more source