Results 181 to 190 of about 171,869 (285)

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

DNA Nanoflower LYTACs Enable Efficient VEGF Degradation and Verteporfin Loading for Combined Therapy of Wet Age‐Related Macular Degeneration

Advanced Science, Volume 13, Issue 16, 18 March 2026.
An integrated approach that combines a DNA nanoflower VEGF degrader with photodynamic therapy is developed for the treatment of wet age‐related macular degeneration, which reduces the risk of VEGF reactivation‐induced CNV recurrence and minimizes the systemic side effects associated with photodynamic therapy.
Mengxuan Li, Yan Yue, Sijin Wu, Xinyu He, Jiayi Song, Shuwen Ma, Haokun Zhang, Chenyu Xu, Song Chen, Yanming Huang, Songbo Xie, Hua Yan   +11 more
wiley   +1 more source

Radiolabeled Vitamins and Nanosystems as Potential Agents in Oncology Theranostics: Developed Approaches and Future Perspectives. [PDF]

J Pers Med
Basirinia G, Comelli A, Alongi P, Ali M, Salvaggio G, Longo C, Di Raimondo D, Tuttolomondo A, Benfante V.   +8 more
europepmc   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

Folate receptor β performs an immune checkpoint function in activated macrophages. [PDF]

Front Immunol
Zhang F, Al-Amin MY, Utturkar S, Jiang R, Cresswell G, Alfar R, Ophaug-Johansen I, Bachman G, Srinivasarao M, Finnell R, Puig-Kröger A, Ratliff T, Low PS.   +12 more
europepmc   +1 more source

Programmed Activatable Photosensitizer for Acidity/Glutathione Dual‐Locked Photodynamic Theranostics of Tumors

Aggregate, Volume 7, Issue 3, March 2026.
A programmed activatable long‐wavelength photosensitizer (LET‐19) integrated an oxazinane moiety and 3,5‐bis(trifluoromethyl)benzenethiol group into the iodinated cyanine skeleton was developed for acidity/glutathione dual‐locked photodynamic theranostics of tumors.
Chao Zhao, Xinlan Lai, Yu Zhang, Shan Lei, Yurong Liu, Peng Huang, Jing Lin   +6 more
wiley   +1 more source

Aerogel Scaffolds: Breathing Life Into Tissue Repair and Companion Diagnostics

Aggregate, Volume 7, Issue 3, March 2026.
Aerogel scaffolds are emerging as multifunctional biomedical platforms that bridge regenerative engineering and molecular diagnostics. By integrating hierarchical porosity, tunable mechanics, and programmable surface chemistry, aerogels can simultaneously support tissue reconstruction and enable localized biomarker sampling and signal transduction ...
Hanlin Zhang, Ruixuan Zheng, Jing Lin, Jiawu Weng, Lexiang Zhang, Fangfu Ye   +5 more
wiley   +1 more source

Folate-Functionalized Polymeric Nanoparticles for 5‑Fluorouracil Delivery to Prostate Cancer: Physicochemical and In Vitro/In Vivo Characterization. [PDF]

ACS Omega
Bhatt B, Kalyankar G, Vyas B, Lalan M, Desai N, Vora LK, Shah P.   +6 more
europepmc   +1 more source

Micro/Nanorobot for Drug Delivery—A Review of Material Selections

Advanced NanoBiomed Research, Volume 6, Issue 3, March 2026.
This review explores material strategies for biomedical micro/nanorobots, emphasizing their roles in propulsion, navigation, drug delivery, and biodegradability. It highlights advancements in metallic, polymeric, and hybrid materials, while addressing clinical translation challenges such as toxicity, immune response, and manufacturability.
Xiaozhuo Wu, Bingyun Li, Malcolm Xing
wiley   +1 more source

Plasma folate dynamics in Plasmodium falciparum-infected African children treated with artemisinin combination therapy and single low-dose primaquine or placebo. [PDF]

Malar J
Ajayi S, Onyamboko MA, Olupot-Olupot P, Ayuen DS, Chimjinda N, Taya C, Williams TN, Uyoga S, Maitland K, Fanello C, Day NPJ, Mukaka M, Taylor WRJ.   +12 more
europepmc   +1 more source