Results 161 to 170 of about 1,914,780 (311)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
LQG/LTR Controller Design Using A Reduced Order Model
, 1989 A specific robust controller design procedure, linear quadratic Gaussian with loop transfer recovery (LQG/LTR), is studied. LQG/LTR design using a reduced-order model is performed.
Rao, Vittal s., Prakash, Rajiva
core +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Linear reduced order modelling for gust response analysis using the DLR-TAU code
, 2013 A unified modelling approach, using computational fluid dynamics, to calculate the flutter stability and dynamic gust response of realistic aircraft models is outlined.
Timme, S., Da Ronch, A., Badcock, K. J.
core
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
New model for vortex-induced vibration of catenary riser
, 2008 This paper presents a new theoretical model capable of predicting the vortex-induced vibration response of a steel catenary riser subject to a steady uniform current.
O'Brien, P. +2 more
core
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Reduced Order Models for the Buckling of Hyperelastic Beams
In this paper, we discuss reduced order modelling approaches to bifurcating systems arising from continuum mechanics benchmarks. The investigation of the beam's deflection is a relevant topic of investigation with fundamental implications on their design for structural analysis and health.
Pichi, Federico, Rozza, Gianluigi
openaire +3 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source