Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
A Reduced Order Model for Sea Water Intrusion Simulation Using Proper Orthogonal Decomposition. [PDF]
Geranmehr M +4 more
europepmc +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
A non-intrusive reduced-order model for finite element analysis of implant positioning in total hip replacements. [PDF]
Reiber M +3 more
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
A reduced order model formulation for left atrium flow: an atrial fibrillation case. [PDF]
Balzotti C +7 more
europepmc +1 more source
The effect of high-speed videoendoscopy configuration on reduced-order model parameter estimates by Bayesian inference. [PDF]
Deng JJ, Hadwin PJ, Peterson SD.
europepmc +1 more source
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Implementation of Principal Component Analysis (PCA)/Singular Value Decomposition (SVD) and Neural Networks in Constructing a Reduced-Order Model for Virtual Sensing of Mechanical Stress. [PDF]
Melgarejo MA +5 more
europepmc +1 more source

