Results 101 to 110 of about 4,522,001 (282)

High Performance Reduced Order Models for Wind Turbines with Full-Scale Converters Applied on Grid Interconnection Studies

Energies, 2014
Wind power has achieved technological evolution, and Grid Code (GC) requirements forced wind industry consolidation in the last three decades. However, more studies are necessary to understand how the dynamics inherent in this energy source interact with
Heverton A. Pereira, Allan F. Cupertino, Remus Teodorescu, Selênio R. Silva   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Reduced Order Modeling of an Industrial Feeder Model

IFAC Proceedings Volumes, 2003
Models of glaes furnaces are described by a set of nonlinear partial differential equâtioris which govern the mass, momentum and energy balances and a numberof non-linear functions of the independent scalais which describe the dependent variables like viscosities and densities in a fluid.
Astrid, P., Weiland, S., Twerda, A.
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Using the Neumann series expansion for assembling Reduced Order Models

Applied and Computational Mechanics, 2014
An efficient method to remove the limitation in selecting the master degrees of freedom in a finite element model by means of a model order reduction is presented.
Nasisi S., Valášek M., Vampola T.
doaj  

Parametric Generation of Datasets for the Creation of Reduced Order Models of Rubber-Metal Elements

Journal of Mechanical Engineering
The work deals with the parametric generation of datasets, which are used for creation of reduced order models (ROM) of rubber-metal elements (RME). First chapter describes the standard development process and advantages of implementing ROM into this ...
Danko Ján, Dobrovolný Juraj, Magdolen Ľuboš, Milesich Tomáš, Kevický Igor, Bernáth Martin, Nemec Tomáš   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Characterizing Wake Behavior of Adaptive Aerodynamic Structures Using Reduced-Order Models

Energies
In recent times, blades that have the ability to change shape passively or actively have garnered interest due to their ability to optimize blade performance for varying flow conditions.
Kyan Sadeghilari, Aditya Atre, John Hall
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source