Results 131 to 140 of about 15,334 (300)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Reducibility of Bolani iron ores and Sinters
, 1962 Reducibility characteristics of Bolani iron ores after its prior beneficiation were studied with hydrogen as a reducing agent at 800° and at 5.3 liters per minute flow rate.
Sankaran, C +2 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Bounded enumeration reducibility and its degree structure
, 2012 We study a strong enumeration reducibility, called bounded enumeration reducibility and denoted by $\leq_{be}$, which is a natural extension of $s$-reducibility $\leq_{s}$.
Sorbi A., Marsibilio D.
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
REDUCIBILITY OF PARABOLICALLY INDUCED REPRESENTATIONS
, 2015 AN ABSTRACT OF THE DISSERTATION OF WAHIDAH ALSIBIANI, for the Doctor of Philosophy degree in MATHEMATICS, presented on MAY 27Th, 2015, at Southern Illinois University Carbondale.
Alsibiani, Wahidah Ali G
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Q-reducibility and m-reducibility on computably enumerable sets
, 2020 © 2014, Pleiades Publishing, Ltd. We study the distinctions between Q-reducibility and m-reducibility on computably enumerable sets. We construct a noncomputable m-incomplete computably enumerable set B such that all computably enumerable sets A ≤QB ...
Batyrshin I.
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