Results 151 to 160 of about 15,334 (300)
On reducibility of linear difference systems
We study problems related to the existence of a nondegenerate substitution(of the Lyapunov type) that reduces a system of linear difference equationsto a system with constant coefficients.
Ali Mahmud Ateiwi
doaj
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Standardized perioperative terminology for emergency cervical cerclage: A framework for feasibility and procedural complexity assessment. [PDF]
Park YJ, Park MI.
europepmc +1 more source
On Truth-Table Reducibility to SAT
We show that polynomial time truth-table reducibility via Boolean circuits to SAT is the same as logspace truth-table reducibility via Boolean formulas to SAT and the same as logspace Turing reducibility to SAT .
Louise Hay, Samuel Buss
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Atlantoaxial Rotatory Fixation: Current Challenges and Advances in Diagnosis and Management. [PDF]
Ren Z, Lan Q, Tian Y, Xu N, Wang S.
europepmc +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Metal-Site Reducibility Governs C-H Activation and PAH Degradation in Ion-Exchanged Bentonite. [PDF]
Jin P +4 more
europepmc +1 more source

