Results 121 to 130 of about 679,415 (356)

Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes

Redox Biology, 2017
Myeloperoxidase produces strong oxidants during the immune response to destroy invading pathogens. However, these oxidants can also cause tissue damage, which contributes to the development of numerous inflammatory diseases. Selenium containing compounds,
Luke Carroll, David I. Pattison, Shanlin Fu, Carl H. Schiesser, Michael J. Davies, Clare L. Hawkins   +5 more
doaj   +1 more source

Asymmetric Synthesis of Atropisomeric Amines via Transaminase‐Catalyzed Dynamic Kinetic Resolution

Advanced Synthesis &Catalysis, EarlyView.
A dynamic kinetic resolution approach is developed for the atroposelective synthesis of heterobiaryl primary amines. Using transaminases and leveraging Lewis acid‐base interactions to induce racemization, a variety of axially chiral primary amines are produced in high yields and enantioselectivities.
Juan M. Coto‐Cid, Patricia Rodríguez‐Salamanca, Christian M. Heckmann, Caroline E. Paul, Joaquín López‐Serrano, Rosario Fernández, José M. Lassaletta, Valentín Hornillos, Gonzalo de Gonzalo   +8 more
wiley   +1 more source

Localization of 3-hydroxy-3-methylglutaryl CoA reductase and 3-hydroxy-3-methylglutaryl CoA synthase in the rat liver and intestine is affected by cholestyramine and mevinolin

Journal of Lipid Research, 1988
In the normal fed rat, both 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) synthase and HMG-CoA reductase are found in high concentrations in hepatocytes that are localized periportally.
A C Li, R D Tanaka, K Callaway, A M Fogelman, P A Edwards   +4 more
doaj   +1 more source

Glyphosate inhibition of ferric reductase activity in iron deficient sunflower roots [PDF]

, 2007
Iron (Fe) deficiency is increasingly being observed in cropping systems with frequent glyphosate applications. A likely reason for this is that glyphosate interferes with root uptake of Fe by inhibiting ferric reductase in roots required for Fe ...
Cakmak, Ismail, Eker, Selim, Gokmen, Ozay Ozgur, Gökmen, Özay Özgür, Ozturk, Levent, Romheld, Volker, Römheld, Volker, Yazıcı, Mustafa Atilla, Yazici, Mustafa Atilla, Çakmak, İsmail, Öztürk, Levent   +10 more
core   +3 more sources

Elderly Liver Grafts are More Susceptible to Ischemia‐Reperfusion After Prolonged Cold Ischemia than Grafts from Young Donors—An Ex Vivo Liver Machine Perfusion Analysis in Sprague Dawley Rats

Advanced Therapeutics, EarlyView.
This study investigates how donor age and cold ischemia time influence liver perfusion parameters and injury markers. Older livers are more susceptible to longer ischemia times displaying more tissue damage, and higher expression of oxidative stress and apoptosis‐related proteins than livers with shorter ischemia times.
Leonard Boerger, Kilian A. Walter, Anna S. Pietsch, Linda Gilles, Oliver Klein, Karl H. Hillebrandt, Joseph M. G. V. Gassner, Jasper Iske, Johann Pratschke, Felix Krenzien, Igor M. Sauer, Nathanael Raschzok, Simon Moosburner   +12 more
wiley   +1 more source

Role of mevalonate in regulation of cholesterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A reductase in cultured cells and their cytoplasts.

Journal of Lipid Research, 1985
H4-II-E-C3 hepatoma cells in culture respond to lipid-depleted media and to mevinolin with increased sterol synthesis from [14C]acetate and rise of 3-hydroxy-3-methylglutaryl coenzyme A reductase levels.
G Popják, C F Clarke, C Hadley, A Meenan   +3 more
doaj   +1 more source

Morphological development and cytochrome c oxidase activity in Streptomyces lividans are dependent on the action of a copper bound Sco protein [PDF]

, 2013
Copper has an important role in the life cycle of many streptomycetes, stimulating the developmental switch between vegetative mycelium and aerial hyphae concomitant with the production of antibiotics.
Calabrese L, Green GN, Holmgren A, Keijser BJ, Kieser TB, van Wezel GP   +5 more
core   +2 more sources

Arabidopsis glutathione‐dependent formaldehyde dehydrogenase is an S‐nitrosoglutathione reductase [PDF]

, 2002
Atsushi Sakamoto, Manami Ueda, Hiromichi Morikawa   +2 more
openalex   +1 more source

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

Advanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang, Lin Lin, Jianting Li, Caihua Li, Shengjun Liang, Xuemei Bai, Fang Wang, Yihua Bao, Dan Guo, Xiaochen Bo, Hao Li, Hebing Chen, Qiu Xie   +12 more
wiley   +1 more source

Development of a noncompetitive, solid phase, bridged biotin-avidin enzyme immunoassay for measurement of human leukocyte microsomal HMG-CoA reductase protein concentration.

Journal of Lipid Research, 1987
Methods were developed for determination of human mononuclear leukocyte HMG-CoA reductase protein concentration by a noncompetitive, solid phase, bridged biotin-avidin enzyme immunoassay procedure.
H J Harwood, Jr, I M Alvarez, Y J Greene, G C Ness, P W Stacpoole   +4 more
doaj   +1 more source