Results 11 to 20 of about 336,111 (290)

RIBONUCLEOTIDE REDUCTASES [PDF]

open access: yesAnnual Review of Biochemistry, 1998
Ribonucleotide reductases provide the building blocks for DNA replication in all living cells. Three different classes of enzymes use protein free radicals to activate the substrate. Aerobic class I enzymes generate a tyrosyl radical with an iron-oxygen center and dioxygen, class II enzymes employ adenosylcobalamin, and the anaerobic class III enzymes
A, Jordan, P, Reichard
openaire   +2 more sources

Determination of the Protein-Protein Interactions within Acyl Carrier Protein (MmcB)-Dependent Modifications in the Biosynthesis of Mitomycin

open access: yesMolecules, 2021
Mitomycin has a unique chemical structure and contains densely assembled functionalities with extraordinary antitumor activity. The previously proposed mitomycin C biosynthetic pathway has caused great attention to decipher the enzymatic mechanisms for ...
Dongjin Leng   +7 more
doaj   +1 more source

The History of mARC

open access: yesMolecules, 2023
The mitochondrial amidoxime-reducing component (mARC) is the most recently discovered molybdoenzyme in humans after sulfite oxidase, xanthine oxidase and aldehyde oxidase. Here, the timeline of mARC’s discovery is briefly described. The story begins with
Bernd Clement, Michel A. Struwe
doaj   +1 more source

Phytophthora capsici sterol reductase PcDHCR7 has a role in mycelium development and pathogenicity

open access: yesOpen Biology, 2022
The de novo biosynthesis of sterols is critical for the majority of eukaryotes; however, some organisms lack this pathway, including most oomycetes. Phytophthora spp.
Weizhen Wang   +6 more
doaj   +1 more source

The Fe Protein: An Unsung Hero of Nitrogenase

open access: yesInorganics, 2018
Although the nitrogen-fixing enzyme nitrogenase critically requires both a reductase component (Fe protein) and a catalytic component, considerably more work has focused on the latter species.
Andrew J. Jasniewski   +3 more
doaj   +1 more source

Chromium bioremediation by Alcaligenes sp. strain newly isolated from chromite mine of Sabzevar [PDF]

open access: yesJournal of Advances in Environmental Health Research, 2017
In this work, CKCr-6A strain was found to be highly resistant to some toxic heavy metals such as Cr+6, Cr+3, Cu+2, Co+2, Cd+2, Pb+2, Hg+2, U+6, tellurium, and selenite. Herein, high chromate tolerance of an isolated strain is reported with a high minimum
Mohsen Mesbahi-Nowrouzi   +2 more
doaj   +1 more source

Modulating Enzyme Function via Dynamic Allostery within Biliverdin Reductase B

open access: yesFrontiers in Molecular Biosciences, 2021
The biliverdin reductase B (BLVRB) class of enzymes catalyze the NADPH-dependent reduction of multiple flavin substrates and are emerging as critical players in cellular redox regulation.
Jasmina S. Redzic   +5 more
doaj   +1 more source

Long-term results of the enzyme glutation system activity in experimental ovarian cancer

open access: yesJournal of Education, Health and Sport, 2022
The article presents the experimental results of the investigation the glutathione system activity (glutathione peroxidase and glutathione reductase) in rats simulated ovarian ascites tumor.
L. Yershova   +4 more
doaj   +1 more source

Influence of Ethylene Signaling in the Crosstalk Between Fe, S, and P Deficiency Responses in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2021
To cope with P, S, or Fe deficiency, dicot plants, like Arabidopsis, develop several responses (mainly in their roots) aimed to facilitate the mobilization and uptake of the deficient nutrient.
María José García   +6 more
doaj   +1 more source

Regulatory Roles of Six-Transmembrane Epithelial Antigen of the Prostate Family Members in the Occurrence and Development of Malignant Tumors

open access: yesFrontiers in Cell and Developmental Biology, 2021
The human six-transmembrane epithelial antigen of the prostate (STEAP) proteins, which include STEAP1–4 and atypical STEAP1B, contain six transmembrane domains and are located in the cell membrane.
Wen-Jia Chen   +6 more
doaj   +1 more source

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