Results 11 to 20 of about 336,111 (290)
RIBONUCLEOTIDE REDUCTASES [PDF]
Ribonucleotide reductases provide the building blocks for DNA replication in all living cells. Three different classes of enzymes use protein free radicals to activate the substrate. Aerobic class I enzymes generate a tyrosyl radical with an iron-oxygen center and dioxygen, class II enzymes employ adenosylcobalamin, and the anaerobic class III enzymes
A, Jordan, P, Reichard
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Mitomycin has a unique chemical structure and contains densely assembled functionalities with extraordinary antitumor activity. The previously proposed mitomycin C biosynthetic pathway has caused great attention to decipher the enzymatic mechanisms for ...
Dongjin Leng+7 more
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The mitochondrial amidoxime-reducing component (mARC) is the most recently discovered molybdoenzyme in humans after sulfite oxidase, xanthine oxidase and aldehyde oxidase. Here, the timeline of mARC’s discovery is briefly described. The story begins with
Bernd Clement, Michel A. Struwe
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Phytophthora capsici sterol reductase PcDHCR7 has a role in mycelium development and pathogenicity
The de novo biosynthesis of sterols is critical for the majority of eukaryotes; however, some organisms lack this pathway, including most oomycetes. Phytophthora spp.
Weizhen Wang+6 more
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The Fe Protein: An Unsung Hero of Nitrogenase
Although the nitrogen-fixing enzyme nitrogenase critically requires both a reductase component (Fe protein) and a catalytic component, considerably more work has focused on the latter species.
Andrew J. Jasniewski+3 more
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Chromium bioremediation by Alcaligenes sp. strain newly isolated from chromite mine of Sabzevar [PDF]
In this work, CKCr-6A strain was found to be highly resistant to some toxic heavy metals such as Cr+6, Cr+3, Cu+2, Co+2, Cd+2, Pb+2, Hg+2, U+6, tellurium, and selenite. Herein, high chromate tolerance of an isolated strain is reported with a high minimum
Mohsen Mesbahi-Nowrouzi+2 more
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Modulating Enzyme Function via Dynamic Allostery within Biliverdin Reductase B
The biliverdin reductase B (BLVRB) class of enzymes catalyze the NADPH-dependent reduction of multiple flavin substrates and are emerging as critical players in cellular redox regulation.
Jasmina S. Redzic+5 more
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Long-term results of the enzyme glutation system activity in experimental ovarian cancer
The article presents the experimental results of the investigation the glutathione system activity (glutathione peroxidase and glutathione reductase) in rats simulated ovarian ascites tumor.
L. Yershova+4 more
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To cope with P, S, or Fe deficiency, dicot plants, like Arabidopsis, develop several responses (mainly in their roots) aimed to facilitate the mobilization and uptake of the deficient nutrient.
María José García+6 more
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The human six-transmembrane epithelial antigen of the prostate (STEAP) proteins, which include STEAP1–4 and atypical STEAP1B, contain six transmembrane domains and are located in the cell membrane.
Wen-Jia Chen+6 more
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