Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Shanghai International Design Center (SHIDC) is a hybrid structure of steel frame and reinforced concrete core tube (SF-RCC). It is a building of unequal height two-tower system and the story lateral stiffness of two towers is different, which may result
Deyuan Zhou +3 more
doaj +1 more source
Treatment of Fracture Head Radius in Children with Closed Reduction and Elastic Nail [PDF]
F. Salama, S. Elshoura, I. Mandour
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Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
The integration of waste carbon fibre materials, specifically shredded prepreg carbon cloth waste (SPCCW) and discarded carbon fibre-reinforced polymer (DCFRP), presents a sustainable and innovative approach to enhancing the structural performance of ...
Umar Ayaz Lone +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Study on Enhancing the Comprehensive Prevention Capability of Marine Disasters in Shandong Province
Shandong Province, one of the regions in China most severely affected by marine disasters, faces multiple challenges including diverse disaster types, extensive geographical distribution, high frequency of occurrence, and significant economic losses ...
JI Chengzhen +5 more
doaj
Determination of the Optimal Number of Strata for Bias Reduction in Propensity Score Matching. [PDF]
Allen Akers
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Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Review of: "Predictive factors of relapse after dose reduction of oral 5-aminosalicylic acid in patients with ulcerative colitis in the remission phase" [PDF]
Grant E. Barber
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