Results 241 to 250 of about 13,343,923 (331)

How I manage luspatercept in transfusion-dependent beta-thalassemia. [PDF]

Hemasphere
Panzieri DL, Scaramellini N, Leoni S, Taher A, Cappellini MD, Motta I.   +5 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Temporal patterns of redisplacement risk following nonoperative treatment of pediatric supracondylar humeral fractures: A retrospective cohort study. [PDF]

J Child Orthop
Zhang J, Li C, Zhao Y.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Efficient Removal of Elemental Mercury from Coal-Fired Flue Gas over Sulfur-Containing Sorbent at Low Temperatures

ACS Omega, 2019
Guopei Zhang, Zhongwei Wang, Lin Cui, Xiaoyang Zhang, Shouyan Chen, Yong Dong   +5 more
doaj   +1 more source

The critical role of isolated Ti³⁺ sites in MIL-125 for photocatalytic nitrate reduction: performance enhancement and deactivation mechanism. [PDF]

Chem Sci
Liao L, Zhao G, Shu R, Wang X, Zhang J, Yuan R.   +5 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Executive Agreements Database, Statement Concerning the Agreement Between The United States and Honduras Regarding the Reduction Of Certain Debts Owed To, Guaranteed By, Or Insured By The United States Government Or Its Agencies. Signed At Tegucigalpa October 7, 2005. Entered Into Force November 28, 2005.

, 2005
Oona A. Hathaway, Curtis A. Bradley, Jack L. Goldsmith   +2 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source