Results 41 to 50 of about 14,661,551 (240)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

A STUDY INTO ICE BUILD-UP AND MELTING ON VERTICAL COOLED PIPES

Holodilʹnaâ Tehnika i Tehnologiâ, 2016
The use of cold accumulators based on the principle of ice build up on the cooled surfaces during off-peak periods and ice melting during on-peak periods is an effective method of electricity bills reduction. Within comparatively short periods of on-peak
Y. Zasiadko, O. Pylypenko, A. Forsiuk, R. Gryshchenko   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Influence of flat tube aspect ratio on melting characteristics of phase change material within a double-tube unit

Case Studies in Thermal Engineering
In this study, a numerical analysis was performed to investigate how the aspect ratio of flat tubes in a double-tube latent thermal energy storage system affects the melting behavior and thermal transfer properties of N-eicosane.
Gwan Gyu Kim, Chan Woo An, Young Min Seo, Seokho Kim, Hoon Ki Choi, Yong Gap Park   +5 more
doaj   +1 more source

Molecular dynamics studies of ultrafast laser-induced phase and structural change in crystalline silicon [PDF]

, 2012
In this work, thermodynamic phenomena in crystalline silicon irradiated by an ultrafast laser pulse were studied using the method of molecular dynamics simulations. The Stillinger-Weber potential was used to model the crystalline silicon. The temperature
Yang, Chengjuan, Xu, Xianfan, Wang, Yaguo   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Numerical analysis of the impact of non-contact fins on the natural convection during melting process

Case Studies in Thermal Engineering
Adding fins is an effective method to accelerate melting proccess. However, fins may not necessarily reduce the melting time due to the negative effects for natural convection.
Zhicheng Zhang, Zuoqin Qian, Lumei Zhao, Qiang Wang, Baolin Wang   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Kinetics of the Synthesis of Aluminum Boride by the Self-Propagating High-Temperature Synthesis Method

Ceramics, 2022
The influence of certain factors on the kinetics of the process of obtaining aluminum borides (burning rate, ingot formation, and phase separation) was investigated. In this study, we report the registration of diboride using the SHS protocol.
Sestager Khusainovich Aknazarov, Alibek Zhumabekovich Mutushev, Juan Maria Gonzalez-Leal, Olga Stepanovna Bairakova, Olga Yuryevna Golovchenko, Natalia Yuryevna Golovchenko, Elena Alexandrovna Ponomareva   +6 more
doaj   +1 more source

Volume reduction of low-level contaminated metal waste by melting: selection of method and conceptual plan [PDF]

, 1978
A review of the literature and prior experience led to selection of induction melting as the most promising method for volume reduction of low-level transuranic contaminated metal waste.
Copeland, G. L., Mateer, R. S., Heestand, R. L.   +2 more
core   +1 more source