Results 61 to 70 of about 14,661,551 (240)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Ore Melting and Reduction in Silicomanganese Production [PDF]
, 2010 The charge for silicomangansese production consists of manganese ore (often mixed with ferromanganese slag) dolomite or calcite, quartz, and in some cases, other additions.
Merete Tangstad +7 more
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Application of enthalpy method for moving boundary problem in laser surface melting
, 1999 A numerical analysis was carried out to study the moving boundary problem in the physical process of pulsed Nd-YAG laser surface melting prior to vaporization.
王会才, 洪友士
core +1 more source
THE EFFECTS OF SELECTIVE LASER MELTING SCAN STRATEGIES ON DEVIATION OF HYBRID PARTS
South African Journal of Industrial Engineering, 2017 The use of additive manufacturing to produce intricate part geometries in the aerospace, medical, and tool-and-die industries is increasingly incorporated in manufacturing process chains.
Hagedorn-Hansen, Devon +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Propulsion and Power ResearchThe melting phenomenon plays a critical role in optimizing the performance of power storage, electronic cooling, and semiconductor devices. The present study aims to analyze the melting effect on the flow of Carreau fluid over a stretchable cylinder ...
Lim Yeou Jiann +5 more
doaj +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Enhancing PCM melting performance through modified fin designs in latent heat thermal storage systems [PDF]
EPJ Web of ConferencesThis numerical study investigates the influence of fin geometry on the melting behavior of PCM (high-density polyethylene, HDPE) within a shell-and-tube latent heat thermal energy storage (LHTES) unit.
Errebii Mohamed +7 more
doaj +1 more source