Results 31 to 40 of about 258,393 (219)
On the Exact Reliability Enhancements of Small Hammock Networks
IEEE Access, 2018 In this paper, we study small hammock networks, more precisely the 29 hammock networks presented by Moore and Shannon in their prescient paper from 1956, where this type of network was introduced.
Simon R. Cowell +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
EFFICIENCY OF REDUNDANT SYSTEM THROUGH CONFIGURATION SUPERVISORS
Надежность и качество сложных систем, 2022 Background. The path to the creation of highly reliable equipment, each separate part of which, due to several factors, has limited reliability, is to develop reconfigurable systems with an excessive number of heterogeneous components. The objective of
А.М. Ageev, V.N. Bukov
doaj +1 more source
Numbers on Thematic Maps: Helpful Simplicity or Too Raw to Be Useful for Map Reading?
ISPRS International Journal of Geo-Information, 2020 As the development of small-scale thematic cartography continues, there is a growing interest in simple graphic solutions, e.g., in the form of numerical values presented on maps to replace or complement well-established quantitative cartographic methods
Jolanta Korycka-Skorupa +1 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The evaluation of redundancy for road traffic networks
Transport, 2016 This paper presents two redundancy indices for road traffic network junctions and also an aggregated network redundancy index. The proposed redundancy indices could be implemented to identify optimal design alternatives during the planning stage of the ...
Rawia Ahmed El-Rashidy +1 more
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2015 The purpose of this paper is to present solution to an ill-posed problem for a muscular internal force feedforward positioning method of a musculoskeletal system. In our previous research, the muscular internal force feedforward positioning method of the
Yuki MATSUTANI +4 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source