Results 71 to 80 of about 172,995 (305)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Distributed position control method for a hyper-redundant modular manipulator

, 2002
According to multi-agent system theory and characteristics of the structural distribution of hyper-redundant modular manipulator, we establish the distributed control system for hyper-redundant modular manipulator.
Tan DL(谈大龙), Liu MY(刘明尧), Jiang, WS   +2 more
core  

Obstacle Avoidance Path Planning of Space Redundant Manipulator Based on a Collision Detection Algorithm

Xibei Gongye Daxue Xuebao, 2020
This paper focuses on the path planning of free-floating space redundant manipulator in an environment with obstacles. Firstly, based on the idea of spherical bounding volume and spatial superposition, the spatial occupying relationship between obstacles

doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Shape control of hyper-redundant modularized manipulator using variable structure regular polygon

, 2004
Hyper-redundant manipulator has more degrees of freedom than the least necessary to perform a given task, thus it has the features of overcoming conventional industrial robot's limitation such as improving its kinematics and dynamic performances ...
Liu JG(刘金国), Ma SG(马书根), Wang YC(王越超), Li B(李斌)   +3 more
core  

Chaotic Vibration Prediction of a Free-Floating Flexible Redundant Space Manipulator

Shock and Vibration, 2016
The dynamic model of a planar free-floating flexible redundant space manipulator with three joints is derived by the assumed modes method, Lagrange principle, and momentum conservation.
Congqing Wang, Linfeng Wu
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Recurrent Neural Network for State Adjustment of Redundant Manipulators

IEEE Access, 2020
To make joints of a redundant manipulator moving automatically to a target state, a state-adjustment (SA) scheme is studied and modified in this paper.
Long Jin, Li He, Zhiguan Huang, Jun Wang
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Research on Hybrid Force Control of Redundant Manipulator with Reverse Task Priority. [PDF]

Materials (Basel), 2022
Su Y, Liu H, Li Y, Xue B, Liu X, Li M, Lin C, Wu X.   +7 more
europepmc   +1 more source