Results 231 to 240 of about 5,500,427 (306)

A reference genome for cultured Drosophila ovarian somatic cells enables studies of transposon and piRNA biology. [PDF]

Genome Biol
Handler D, Brennecke J.
europepmc   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

MarpolBase: genome database for Marchantia polymorpha featuring high quality reference genome sequences. [PDF]

Plant Cell Physiol
Tanizawa Y, Mochizuki T, Yagura M, Sakamoto M, Fujisawa T, Kawamura S, Shimokawa E, Yamaoka S, Nishihama R, Bowman JL, Berger F, Yamato KT, Kohchi T, Nakamura Y.   +13 more
europepmc   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Exome Sequencing in Pacific Islanders With Nephropathies of Unknown Origin

Kidney International Reports
David de Saint Gilles, Nicolas Quirin, Yannis Lombardi, Thomas Lamy, Yann Butté, Antoine Biron, Marine Dancer, Laure Raymond, Laurent Mesnard, Alice Doreille   +9 more
doaj   +1 more source

Ring chromosomes uncovered by optical genome mapping: impact of telomeric-associated regions and reference genome selection on structural variant interpretation. [PDF]

Chromosome Res
Burssed B, Oliveira ARCP, Bellucco FT, Melaragno MI.   +3 more
europepmc   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier, Françoise Heran, Francis Lallemand, Pierre Bourdillon   +3 more
wiley   +1 more source

The diploid reference genome of a human embryonic stem cell line

Pačar I, Ungaro MT, Chen Y, Dallali H, Medico JA, Hebbar P, Diekhans M, Di Tommaso E, Geleta M, Chan PP, Lowe TM, Balacco J, Jain N, Ackerman F, Mochi M, Ioannidis AG, Sawarkar N, Diaz K, Krishna Sudhakar K, Powell JE, Jain M, Rosa A, Croft GF, Tanzer A, Jarvis ED, Formenti G, Salama SR, Giunta S.   +27 more
europepmc   +1 more source

A reference genome for Colusa grass, Neostapfia colusana, a threatened and endangered California vernal pool plant. [PDF]

J Hered
Pennington LK, Escalona M, J Toews D, Chumchim N, Cooper R, Fairbairn CW, Marimuthu MPA, Miller C, Nguyen OH, Ruiz-Ramos D, Seligmann WE, Stephens M, Toffelmier E, Shaffer HB, Meyer RS, Sexton JP.   +15 more
europepmc   +1 more source

The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti, Sheena Waters, Adil Harroud, Pernilla Stridh, Ruth Dobson, Benjamin M. Jacobs   +5 more
wiley   +1 more source