Results 281 to 290 of about 5,571,829 (332)

ERGA-BGE reference genome of <i>Eunicella cavolini,</i> an IUCN Near Threatened Gorgonian of the Mediterranean Sea. [PDF]

Open Res Eur
Aurelle D, Guillemain D, Zuberer F, Malengros D, Böhne A, Monteiro R, Marcussen T, Struck TH, A Oomen R, Genoscope Sequencing Team, Moussy A, Cruaud C, Labadie K, Demirdjian L, Belser C, Wincker P, H Oliveira P, Aury JM, Bortoluzzi C.   +18 more
europepmc   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

An updated reference genome of Barbatula barbatula (Linnaeus, 1758). [PDF]

Sci Data
Laczkó L, Nagy NA, Nagy Á, Maroda Á, Sály P.   +4 more
europepmc   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

A reference genome for Trichogramma kaykai: a tiny desert-dwelling parasitoid wasp with competing sex-ratio distorters. [PDF]

G3 (Bethesda)
Culotta JA, Lindsey ARI.
europepmc   +1 more source

Associations of Sleep and Shift Work with Osteoarthritis Risk

Arthritis Care &Research, Accepted Article.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships between circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000‐person cohort, we evaluated associations between sleep duration, sleeplessness/insomnia, and ...
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Hybrid reference genome assembly for the archetypal <i>Leishmania (Viannia) guyanensis</i> bearing the dsRNA totivirus LRV1. [PDF]

Microbiol Resour Announc
Myler PJ, Ramasamy G, Warren WC, Dobson DE, Beverley SM.   +4 more
europepmc   +1 more source

What Do Large Language Models Know About Materials?

Advanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer, Thomas Wallmersperger, Gianaurelio Cuniberti   +2 more
wiley   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Hybrid reference genome assemblies for <i>Leishmania (Viannia) braziliensis</i>, a primary agent of mucocutaneous leishmaniasis. [PDF]

Microbiol Resour Announc
Cotton JA, Van den Broeck F, Myler PJ, Akopyants NS, Berriman M, Beverley SM.   +5 more
europepmc   +1 more source