Results 81 to 90 of about 5,500,427 (306)

Whole-Genome Sequence of a European Clone II and OXA-72-Producing Acinetobacter baumannii Strain from Serbia. [PDF]

open access: yes, 2015
We report here the draft genome sequence of a carbapenem-resistant Acinetobacter baumannii strain isolated from a patient, a strain which previously stayed in Serbia. This isolate possessed the blaOXA-72 carbapenemase gene.
Imanci, D   +13 more
core   +1 more source

Improving Imputation Quality in BEAGLE for Crop and Livestock Data

open access: yesG3: Genes, Genomes, Genetics, 2020
Imputation is one of the key steps in the preprocessing and quality control protocol of any genetic study. Most imputation algorithms were originally developed for the use in human genetics and thus are optimized for a high level of genetic diversity ...
Torsten Pook   +6 more
doaj   +1 more source

Ocean Genomes: reference genome resources for marine vertebrates. [PDF]

open access: yesNPJ Biodivers
Abstract We present Ocean Genomes, a program dedicated to producing reference genome resources to facilitate improved monitoring approaches and management outcomes for marine vertebrate biodiversity. Ocean Genomes will generate high-quality reference genomes of representatives of all marine vertebrate families and additional high-conservation-
Parata L   +13 more
europepmc   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Draft genome sequence of Komagataeibacter rhaeticus Strain AF1, a high producer of cellulose, isolated from kombucha tea

open access: yes, 2014
Here, we present the draft genome sequence of Komagatabaeicter rhaeticus strain AF1, which was isolated from Kombucha tea and is capable of producing high levels of cellulose.Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Laboratório ...
Santos, Renato Augusto Corrêa dos   +10 more
core   +1 more source

The reference genome sequence of Artemisia argyi provides insights into secondary metabolism biosynthesis

open access: yesFrontiers in Plant Science
Artemisia argyi, a perennial herb of the genus Artemisia in the family Asteraceae, holds significant importance in Chinese traditional medicine, referred to as “Aicao”. Here, we report a high-quality reference genome of Artemisia argyi L. cv. beiai, with
Xinqiang Gao   +9 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Leveraging the T2T assembly to resolve rare and pathogenic inversions in reference genome gaps [PDF]

open access: yes
Chromosomal inversions (INVs) are particularly challenging to detect due to their copy-number neutral state and association with repetitive regions. Inversions represent about 1/20 of all balanced structural chromosome aberrations and can lead to disease
Sedlazeck, Fritz J.   +49 more
core   +1 more source

De Novo Genome Assembly for an Endangered Lemur Using Portable Nanopore Sequencing in Rural Madagascar

open access: yesEcology and Evolution
As one of the most threatened mammalian taxa, lemurs of Madagascar are facing unprecedented anthropogenic pressures. To address conservation imperatives such as this, researchers have increasingly relied on conservation genomics to identify populations ...
Lindsey Hauff   +6 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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