Results 41 to 50 of about 12,282,811 (238)

Genotypic resistance testing improves antiretroviral treatment outcomes in a cohort of adolescents in Cameroon: Implications in the dolutegravir‑era

Journal of Public Health in Africa, 2023
Poor internet infrastructure limits the use of computer-based nursing process forms in rural areas. This study aimed to configure a computer‑based nursing process form to support nursing diagnosis and care evaluation in rural healthcare clinics in Africa.
Willy L.R.T. Pabo, Debimeh Njume, Roland N. Ndip, Desiré Takou, Maria-Mercedes Santoro, Collins Chenwi, Grace Beloumou, Ezechiel N.J. Semengue, Alex D. Nka, Aude C. Ka'e, Georges Teto, Beatrice Dambaya, Sandrine Djupsa, Raymond B. Nyasa, Davy H.G. Anguechia, Cedric Kamta, Lionel Bala, Virginie Lambo, Samuel M. Sosso, Vittorio Colizzi, Carlo F. Perno, Joseph Fokam, Alexis Ndjolo   +22 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Interoperability of two commercial kits in detecting high oncogenic human papilloma virus and genetic diversity in Cameroon: implications for cervical cancer screening strategies in resource-limited settings

Infectious Agents and Cancer
Background Cameroon lacks a national screening algorithm for Human papilloma virus (HPV) infection. In order to standardize HPV screening using molecular detection tools in Cameroon, this study aimed to evaluate the concordance of HPV detection via two ...
Michel Carlos Tommo Tchouaket, Jeremiah Efakika Gabisa, Ezechiel Ngoufack Jagni Semengue, Larissa Gaelle Moko Fotso, Valentine Marie Ferré, Bernadette Fokou Bomgning, Keriane Diane Kambou Kountchou, Alex Durand Nka, Nadine Nguendjoung Fainguem, Yagai Bouba, Désiré Takou, Rachel Kamgaing, Aude Christelle Ka’e, Collins Ambe Chenwi, Samuel Martin Sosso, Charlotte Charpentier, Carlo-Federico Perno, Vittorio Colizzi, Fon Wilfred Mbacham, Joseph Fokam, Alexis Ndjolo   +20 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Low burden of clinically relevant anaemia and thrombocytopenia among adolescents living with HIV receiving tenofovir/lamivudine plus dolutegravir: the CIPHER-ADOLA study in Cameroon

AIDS Research and Therapy
Background Anaemia and thrombocytopenia adversely affect adolescent HIV outcomes, yet adolescent-specific data from the tenofovir/lamivudine/dolutegravir (TLD) era remain scarce, and access to full blood count (FBC) testing is limited in Cameroon.
Nadine Nguendjoung Fainguem, Yagai Bouba, Rachel Kamgaing, Jeremiah Efakika Gabisa, Aude Christelle Ka’e, Michel Carlos Tommo Tchouaket, Alex Durand Nka, Cynthia Ayafor, Lum Forgwei, Nelly Kamgaing, Suzie Ndiang Tetang, Francis Ndongo Ateba, Desire Takou, Dominik Guebiapsi Tameza, Félicité Noukayo, Alice Ketchaji, Ezechiel Ngoufack Jagni Semengue, Wome Basseck Roland, Wiadamong Agabus, Abdou Rahamani Gnambi, Catherine Eyenga, Naomi Karell Etame, Aurelie Minelle Kengni Ngueko, Larissa Gaëlle Moko Fotso, Junie Flore Yimga, Krystel Nomo Zam, Annie Nga Motaze, Collins Ambe Chenwi, Grace Anong Beloumou, Sandrine Claire Djupsa Njdeyep, Upal Roy, Rogers Awoh Ajeh, Anne Esther Njom Nlend, Paul Ndombo Koki, Hyppolite Kuekou Tchidjou, Daniele Armenia, Maria Mercedes Santoro, Francesca Ceccherini-Silberstein, Samuel Martin Sosso, Alexis Ndjolo, Vittorio Colizzi, Carlo-Federico Perno, Joseph Fokam   +42 more
doaj   +1 more source