Results 71 to 80 of about 5,447,975 (305)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Estabilidad de un suero control multienzimático utilizado como material de referencia en los laboratorios clínicos Stability of a multienzyme control serum used as reference material in clinical laboratories

Revista Cubana de Investigaciones Biomédicas, 2012
Una de las vías fundamentales para garantizar la calidad de los ensayos realizados en los laboratorios clínicos es mediante el uso de materiales de referencia.
Oscar Hernández Betancourt, Sandra Fernández Torres, Nayadis Vázquez Reyes, Lydice Leiva Quesada, Yadira Falcón Almeida, Ubaldo Torres Romo   +5 more
doaj  

Characterization of Ricin and R. communis Agglutinin Reference Materials

Toxins, 2015
Ricinus communis intoxications have been known for centuries and were attributed to the toxic protein ricin. Due to its toxicity, availability, ease of preparation, and the lack of medical countermeasures, ricin attracted interest as a potential ...
Sylvia Worbs, Martin Skiba, Martin Söderström, Marja-Leena Rapinoja, Reinhard Zeleny, Heiko Russmann, Heinz Schimmel, Paula Vanninen, Sten-Åke Fredriksson, Brigitte G. Dorner   +9 more
doaj   +1 more source

Scalar Material Reference Systems and Loop Quantum Gravity

, 2012
In the past, the possibility to employ (scalar) material reference systems in order to describe classical and quantum gravity directly in terms of gauge invariant (Dirac) observables has been emphasised frequently.
Giesel, Kristina, Thiemann, Thomas
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Titanite U-Pb dating by LA-Quadrupole-ICP-MS: analytical procedures and applications to Rhyacian metamorphic rocks of the Southeastern Guiana Shield [PDF]

Anais da Academia Brasileira de Ciências
We present a comprehensive set of LA-Q-ICP-MS U-Pb ages on titanite standards (Tory Hill, Khan, Mud Tank, and CKHB titanites) together with samples from the Southeastern Guiana Shield, as a geological application of the method implemented at the Pará-Iso
JOÃO ALBERTO E. PINTO, JEAN MICHEL LAFON, JOÃO M. MILHOMEM NETO, KEI SATO   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Development of alumina-based porosity reference materials for the mercury porosimetry method

Стандартные образцы, 2020
This paper presents the results of a study on the development of alumina-based porosity reference materials (RMs), which are intended for controlling the accuracy of the measurement results obtained using the mercury porosimetry method.
E. P. Sobina
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Nonparametric estimation of the heterogeneity of a random medium using Compound Poisson Process modeling of wave multiple scattering

, 2009
In this paper, we present a nonparametric method to estimate the heterogeneity of a random medium from the angular distribution of intensity transmitted through a slab of random material.
Bihan, Nicolas Le, Margerin, Ludovic
core   +4 more sources