Results 101 to 110 of about 11,306,421 (294)

Outstanding Business Reference Sources: The 2005 Selection of Recent Titles

, 2006
A selection of business reference sources for ...
BRASS Business Reference Sources Committee
core  

Definition of Reference 2021

, 2021
To update the 2008 version and to extend the conception of reference work beyond the ...
Reference Services Section (RSS) Executive Committee
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

«CSOVV» LTD AND ITS CONTRIBUTION TO ENSURING THE TRACEABILITY OF THE MEASUREMENT RESULTS OF WATERS SAFETY AND QUALITY PARAMETERS

Стандартные образцы, 2017
The article presents information about one of the largest in RF manufacturer of the approved types reference materials (GSO), intended for the metrological assurance of safety and quality parameters control for water, aqueous medium and different types ...
A. N. Atanov, O. V. Boldina, S. V. Gagarinov, Iu. V. Kuzental', L. S. Sidorova   +4 more
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Harmonising ctDNA Measurement in Haematological Malignancies: Traceability, Commutability and Reporting

Diagnostics
Circulating tumour DNA (ctDNA) assays are increasingly applied in haematological malignancies for non-invasive genotyping, quantitative response assessment, measurable residual disease (MRD) detection, and relapse surveillance, often complementing bone ...
Sapha Shibeeb
doaj   +1 more source

Outstanding Business Reference Sources: The 2008 Selection of Recent Titles

, 2009
A selection of business reference sources for ...
BRASS Business Reference Sources Committee
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Outstanding Business Reference Sources: The 2011 Selection of Recent Titles

, 2012
A selection of business reference sources for ...
BRASS Business Reference Sources Committee
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source