Results 81 to 90 of about 18,500,807 (388)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Reference materials in biomedical research
Стандартные образцы, 2017 The paper represents general information of use of reference material (RM) of composition of toxic metal solutions and RM of composition of biological tissues which contain toxic metals (TM) when measuring the TM content in biological materials.
A. M. Malov
doaj +1 more source
IFMIF suitability for evaluation of fusion functional materials [PDF]
, 2011 The International FusionMaterials Irradiation Facility (IFMIF) is a future neutron source based on the D-Li stripping reaction, planned to test candidate fusionmaterials at relevant fusion irradiation conditions.
A. García +25 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Digital signal processing application in nuclear spectroscopy [PDF]
Ядерна фізика та енергетика, 2009 Digital signal processing algorithms for nuclear particle spectroscopy are described along with a digital pile-up elimination method applicable to equidistantly sampled detector signals pre-processed by a charge-sensitive preamplifier.
O. V. Zeynalova +3 more
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Recent advances in electrochemical analysis of phenylurea herbicides
Sensors and Actuators ReportsPhenylurea herbicides (PUHs) are extensively used in modern agriculture due to their high efficiency in weed control; however, their widespread application has led to persistent environmental contamination and growing public health concerns.
Ranil C. T․ Temgoua +2 more
doaj +1 more source
Stable isotopes in diatom silica [PDF]
, 2010 Diatom silica is a form of biogenic opal (SiO2.nH2O, Figure 1) containing oxygen, silicon, carbon and nitrogen isotopes that can be used in lacustrine and marine paleoenvironmental studies.
Leng, Melanie J., Swann, George E.A.
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source