Results 271 to 280 of about 9,933,382 (352)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Characterization of Particulate Emission from Animal Feeding Operations with Three-wavelength Lidar Using Simultaneous In-Situ Point Measurements as Calibration Reference Sources

, 2006
Vladimir V. Zavyalov, Gail E. Bingham, Thomas D. Wilkerson, Jason Swasey, Christian C. Marchant, Christopher Rogers, Randy S. Martin, Philip J. Silva, Vishal Doshi   +8 more
openalex   +1 more source

The crustal movement velocity at the seafloor reference point 'Sagami Bay' detected by seafloor geodetic observation

, 2008
Hiroaki Saito, Geophysics Office
openalex   +1 more source

Wheel Slip Equilibrium Point Model Reference Adaptive Control Based PID Controller for Antilock Braking System: A New Approach

Paulinus Eze, D O Njoku, O C Nwokonkwo, C G Onukwugha, J. N. Odii, Janefrances E. Jibiri   +5 more
openalex   +2 more sources

Transformation for point rotation reference frames

, 2013
Boris V. Gisin
openalex   +1 more source

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PQA-Net: Deep No Reference Point Cloud Quality Assessment via Multi-View Projection

IEEE transactions on circuits and systems for video technology (Print), 2021
Recently, 3D point cloud is becoming popular due to its capability to represent the real world for advanced content modality in modern communication systems.
Qi Liu, Hui Yuan, Honglei Su, Hao Liu, Yu Wang, Huan Yang, Junhui Hou   +6 more
semanticscholar   +1 more source

Dynamic Transfer Reference Point-Oriented MOEA/D Involving Local Objective-Space Knowledge

IEEE Transactions on Evolutionary Computation, 2022
The decomposition-based evolutionary algorithm (MOEA/D) has attained excellent performance in solving optimization problems involving multiple conflicting objectives.
Yingbo Xie, Shengxiang Yang, Ding Wang, Jun-Li Qiao, Baocai Yin   +4 more
semanticscholar   +1 more source

The Effects of Agency Assignment and Reference Point on Responses to COVID-19 Messages

Health Communication, 2020
As the COVID-19 pandemic poses severe threats to human life around the globe, effective risk messages are needed to warn the public and encourage recommended actions for avoiding infection, especially as steps are taken to ease physical restrictions and ...
Haijing Ma, Claude H. Miller
semanticscholar   +1 more source

Goals as Reference Points

Cognitive Psychology, 1999
We argue that goals serve as reference points and alter outcomes in a manner consistent with the value function of Prospect Theory (Kahneman & Tversky, 1979; Tversky & Kahneman, 1992). We present new evidence that goals inherit the properties of the value function-not only a reference point, but also loss aversion and diminishing sensitivity.
C, Heath, R P, Larrick, G, Wu
openaire   +2 more sources

The Ties That Unbind: Socialization and Business-Owning Family Reference Point Shift

Academy of Management Review, 2019
Existing theory describes how family firms utilize a unique socioemotional reference point to frame strategic decision making, but scholars have not fully considered family-level strategy or change...
Robert S. Nason, A. Mazzelli, M. Carney
semanticscholar   +1 more source