Results 91 to 100 of about 3,126,236 (305)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Finding Meaning in the Madness: Unifying Your Library’s Data Collection with LibAnalytics [PDF]
, 2015 Libraries have collected data across multiple platforms and areas and developed reports to inform their stakeholders to show the value of the library. As data collection methods have evolved, more assessment platforms have become available in the market.
Singh, Madhu
core +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Evaluating e-Government services from a citizens' prespective: A reference process model [PDF]
, 2012 Evaluating and optimizing e-government services is imperative for governments especially due to the capacity of e-services to transform public administrations and assist the interactions of governments with citizens, businesses and other government ...
Irani, Z +6 more
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Beta Spaces as a Model for Recontextualizing Reference Services in Libraries
In the Library with the Lead Pipe, 2016 In Brief: Reference services are at a cross-roads. While many academic libraries continue to offer reference services from behind a desk, others are moving to roving and embedded reference models.
Madelynn Dickerson
doaj
Readers’ advisory guide development for webtoon
Information Research: An International Electronic JournalIntroduction. Readers’ advisory (RA) services are one of the core information services that libraries provide. As the types and formats of the collection materials have diversified, relevant RA services have evolved accordingly. This project develops an
Hyerim Cho +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Provision of digital reference services in academic libraries in Kenya: a review
Regional Journal of Information and Knowledge Management, 2017 Rationale of the study - The popularity of internet as an avenue of communication and source of information has led to decreasing numbers of in-person reference transaction in academic libraries.
James M. Tutu
doaj
Implementation Science CommunicationsBackground Neovascular age-related macular degeneration (nAMD) is one of the largest single-disease contributors to hospital outpatient appointments. Challenges in finding the clinical capacity to meet this demand can lead to sight-threatening delays in ...
Henry David Jeffry Hogg +5 more
doaj +1 more source