Results 121 to 130 of about 3,126,236 (305)

Holistic 360 Reference Services

Pennsylvania Libraries: Research & Practice
This study focuses on how academic libraries face ongoing challenges in adapting to emerging technologies and external events like the COVID-19 pandemic.
Lisa Rand, John Shank
doaj   +1 more source

Annotated Bibliography: The Reference Desk: Grand Idea or Gone Down the River?

, 2018
This bibliography is from a panel presentation at the 2017 ACL Conference. The goal of this panel was to explore different rationales or sets of values that illustrated the continuation of the reference desk and reference service as essential to the ...
Jones, Alison, McCoy, Erin, Rice, Amy C., Walz, Jennifer L.   +3 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Online reference services : overview of their development in theory and practice [PDF]

, 2010
Online referentne usluge, u svom najopćenitijem obliku, predstavljaju referentne usluge u mrežnom okruženju. U radu je dan sažet pregled razvoja online referentnih usluga od njihovih početaka pa sve do danas.
Boris Bosančić
core   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Use of Subimages in Fish Species Identification: A Qualitative Study [PDF]

, 2011
Many scholarly tasks involve working with subdocuments, or contextualized fine-grain information, i.e., with information that is part of some larger unit.
Delcambre, Lois, Fox, Edward, Hallerman, Eric, Murthy, Uma, Pérez-Quiñones, Manuel, Torres, Ricardo, Tzy Li, Lin   +6 more
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

A survey of intrusion detection system technologies [PDF]

, 2016
This paper provides an overview of IDS types and how they work as well as configuration considerations and issues that affect them. Advanced methods of increasing the performance of an IDS are explored such as specification based IDS for protecting ...
Heenan, Ross, Moradpoor, Naghmeh
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source