Results 101 to 110 of about 8,013 (292)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The semantic significance of Donnellan's referential/attributive distinction
grantor: University of TorontoIn "Reference and Definite Descriptions", Keith Donnellan introduces the notion of referential and attributive uses of definite descriptions--phrases such as "the author of Waverly".
Hunter, Andrew John
core
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A study in referential coherence: Chinese writers of English
Chinese writers of English often have problems in making their text coherent. This study is aimed to find out the possible factors in weakening coherence in their English essays.
Li, H.,
core
O Livro Azul sobre o solipsismo e os usos do ‘Eu’: Uma leitura dialética
This paper argues for a dialectical reading of Wittgenstein’s grammatical reminders concerning the uses of the first person pronoun in The Blue Book. Against a widespread, ‘non-referential’ view which takes those reminders as direct attempts
Jônadas Techio
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A NUMERICAL STUDY OF WATER PROPAGATION AND BREAKING USING SPH METHOD [PDF]
A breaking wave is a violent natural event that involves highly complex phenomena, such as large deformation of free surface, turbulence, vortex generation, strong interaction between wave and structures, etc.
COELHO J. G. +3 more
doaj
Metaphorical Singular Reference. The Role of Enriched Composition in Reference Resolution
It is widely accepted that, in the course of interpreting a metaphorical utterance, both literal and metaphorical interpretations of the utterance are available to the interpreter, although there may be disagreement about the order in which these ...
Anne Bezuidenhout
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source

