Results 91 to 100 of about 2,511,094 (288)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Referential inconstancy in natural language
There is a lively debate between proponents of referentialist and predicativist semantics about the nature of proper names in natural language. Still, the assumption that bare singular (referential) uses of proper names in argument position of a ...
García Ramírez, Eduardo
core +1 more source
The Speech Act of Naming in Fictional Discourse
Studia Semiotyczne, 2022 DOI: https://doi.org/10.26333/sts.xxxvi1.08 This paper argues that García-Carpintero’s theory of proper names (the Mill-Frege theory) and his theory of fiction-making do not work well together.
Amalia Haro Marchal
doaj
Où est "ailleurs" ? Sémantique lexicale de l'adverbe spatial "ailleurs".
Corela, 2013 Like other words, we think that the French spatial adverbial ailleurs contains two kinds of information: a conceptual meaning and a procedural meaning that depends on the semantico-referential process it involves. This article postulates that ailleurs is
Marie Lammert
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Ordering adjectives in referential communication [PDF]
, 2018 We contrasted two hypotheses concerning how speakers determine adjective order during referential communication. The discriminatory efficiency hypotheses claims that speakers place the most discriminating adjective early to facilitate referent ...
Kumiko Fukumura, Fukumura, Kumiko
core +1 more source
Using Referential Language Games for Task-oriented Ontology Alignment
, 2022 Ontology Alignment (OA) is generally performed by requesting two parties to provide their complete knowledge to a third party that suggests potential schema alignments. This might however not always be possible or helpful, as for example, when two organisations want to query each other’s knowledge, and none of them is willing to share their schema due ...
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Epistemological Foundation for the Use of the Linguistic Measures of the Referential Process
Journal of Psycholinguistic ResearchAbstract The analysis of epistemological beliefs underlying psychotherapeutic interventions has been largely neglected by research in psychotherapy, training in psychotherapy and psychology, and often by theorists of different clinical orientations.
Attà Negri, Arianna Barazzetti
openaire +3 more sources