Results 61 to 70 of about 8,013 (292)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Marked Referential Practices in English Conversation [PDF]

open access: yes, 2005
This paper considers various marked practices by which speakers of English refer to people, including themselves and others, when conversing with their interlocutors.
Oh, Sun-Young
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

“Are we up to the task?”: exploring the syntactic and semantic frontiers of X be up to Y and other aspectual-modal idioms

open access: yesAnglophonia
This paper aims to characterize X be up to Y, an idiom associated with four different syntactic and referential constructions, each associated with distinct yet related aspectual and modal meanings.
Manon Philippe
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Referential inconstancy in natural language

open access: yes
There is a lively debate between proponents of referentialist and predicativist semantics about the nature of proper names in natural language. Still, the assumption that bare singular (referential) uses of proper names in argument position of a ...
García Ramírez, Eduardo
core   +1 more source

Noise Reduction in Time Domain Using Referential Reconstruction

open access: yesIEICE Transactions on Information and Systems, 2006
We present a novel approach for single-channel noise reduction of speech signals contaminated by additive noise. In this approach, the system requires speech samples to be uttered in advance by the same speaker as that of the input signal. Speech samples used in this method must have enough phonetic variety to reconstruct the input signal.
Takehiro Ihara   +3 more
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Attributive-Referential Distinction and Uses of Definite Descriptions

open access: yes, 2014
The paper discusses various uses of definite descriptions. The aim is to demon-strate that the commonly adopted Donnellan’s dichotomous division into “attributive” and “referential” uses is inadequate.
Rostworowski, Wojciech
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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